Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.43 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644957 | 0.84 | TRPA1 (0.47) | FFAR1FFAR4ADAMTS4MMP13CTSL | |
| SCHEMBL1680222 | 0.84 | TRPA1 (0.47) | FFAR1FFAR4ADAMTS4MMP13CTSL | |
| SCHEMBL12807428 | 0.83 | FFAR1 (0.41) | FFAR1FFAR4CNR1ADAMTS4CNR2 | |
| SCHEMBL12735745 | 0.83 | GLA (0.42) | FFAR1FFAR4CNR1ADAMTS4CNR2 | |
| SCHEMBL14726008 | 0.78 | HTRA1 (0.42) | FFAR1FFAR4CNR1ADAMTS4CNR2 | |
| SCHEMBL19249056 | 0.78 | CNR1 (0.54) | FFAR1FFAR4CNR1CNR2LMNA | |
| SCHEMBL5263129 | 0.77 | GLA (0.54) | CNR1CNR2LMNAGLAMEP1A | |
| SCHEMBL3491515 | 0.75 | FFAR1 (0.72) | FFAR1FFAR4CNR1LMNA | |
| SCHEMBL6364918 | 0.74 | FFAR1 (0.55) | FFAR1FFAR4CNR1LMNAGLA | |
| SCHEMBL7335965 | 0.74 | FFAR1 (0.57) | FFAR1FFAR4CNR1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1511734-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2006-05-10 | — | — | EP | disclosed |
| EP-1511734-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2005-03-09 | — | — | EP | disclosed |
| WO-2003088903-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2003-10-30 | — | — | WO | disclosed |