Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5466444 | 0.84 | MAPT (0.38) | MAPTBCHESLC6A3 | |
| SCHEMBL5779483 | 0.83 | BCHE (0.33) | MAPTBCHESLC6A3 | |
| SCHEMBL5778551 | 0.77 | MAPT (0.37) | MAPTBCHEKIF11SLC6A3 | |
| SCHEMBL8172914 | 0.77 | MAPT (0.37) | MAPT | |
| SCHEMBL5777952 | 0.74 | HTR2B (0.36) | MAPT | |
| SCHEMBL5777073 | 0.70 | RAB9A (0.56) | MAPT | |
| SCHEMBL4809592 | 0.69 | RAB9A (0.38) | MAPT | |
| SCHEMBL21854492 | 0.69 | SLC6A3 (0.38) | SLC6A3 | |
| SCHEMBL5777255 | 0.68 | MAPT (0.36) | MAPTKIF11 | |
| SCHEMBL5778922 | 0.68 | SLC6A3 (0.31) | MAPTSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | MAPT 94/4885BCHE 1199/4885KIF11 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.