SCHEMBL5778918

SCHEMBL5778918

Oc1nc2ncncc2c(Cl)c1-c1ccc(F)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4718820 0.66
Hydrochloric Acid SCHEMBL27493563 0.64 CYP11B2 (0.40) CYP17A1CYP11B1CYP11B2
SCHEMBL2796953 0.62 EGFR (0.38) CYP11B1
SCHEMBL27997963 0.61 GRIN2B (0.40)
SCHEMBL6219693 0.60 ALOX5AP (0.39) CYP17A1CYP3A4CYP11B1CYP11B2
SCHEMBL5716618 0.60 CTSL (0.44)
Hydrochloric Acid SCHEMBL27493969 0.59 ALOX5AP (0.38) CYP17A1CYP3A4CYP11B1CYP11B2
SCHEMBL30047586 0.59 EGFR (0.38) CYP11B2
Hydrochloric Acid SCHEMBL28757672 0.59 CTSL (0.33)
SCHEMBL3976111 0.59 PIK3CD (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1648890-A2 ARYL-CONDENSED 3-ARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2006-04-26 EP disclosed
WO-2005010000-A2 ARYL-CONDENSED 3-ARYLPYRIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING PATHOGENIC FUNGI BASF AKTIENGESELLSCHAFT (DE) 2005-02-03 WO disclosed