Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778933 | 1.00 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2KDM4E | |
| SCHEMBL5779868 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL5779864 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1MAPK1SMN1; SMN2KDM4ETAAR1 | |
| SCHEMBL9593033 | 0.75 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EXPO1 | |
| SCHEMBL5780538 | 0.73 | — | — | |
| SCHEMBL5780531 | 0.73 | — | — | |
| SCHEMBL5780529 | 0.73 | — | — | |
| SCHEMBL21174020 | 0.73 | SLC6A12 (0.33) | ALDH1A1L3MBTL1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5775558 | 0.72 | — | — | |
| SCHEMBL5775563 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631570-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | Abbott Laboratories (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004083207-A1 | NAPHTHYRIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | ABBOTT LABORATORIES (US) | 2004-09-30 | — | — | WO | disclosed |