Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL309484 | 0.83 | ALDH1A1 (0.48) | ALDH1A1UNGNFE2L2CYP2A6SRC | |
| SCHEMBL6848985 | 0.83 | ALDH1A1 (0.48) | ALDH1A1UNGNFE2L2CYP2A6CA12 | |
| SCHEMBL29846591 | 0.83 | ALDH1A1 (0.48) | ALDH1A1UNGNFE2L2CYP2A6SRC | |
| SCHEMBL15352523 | 0.80 | ALDH1A1 (0.45) | ALDH1A1UNGNFE2L2CYP2A6CA12 | |
| SCHEMBL1111336 | 0.80 | ALDH1A1 (0.45) | ALDH1A1UNGNFE2L2CYP2A6FBP1 | |
| SCHEMBL16032971 | 0.80 | TP53 (0.50) | ALDH1A1NFE2L2FBP1TTRPIM1 | |
| SCHEMBL6854509 | 0.80 | ESR1 (0.52) | ALDH1A1UNGNFE2L2CYP2A6SRC | |
| SCHEMBL3509619 | 0.80 | UNG (0.46) | ALDH1A1UNGNFE2L2CYP2A6CA12 | |
| SCHEMBL5015049 | 0.79 | TAAR1 (0.52) | ALDH1A1UNGNFE2L2CYP2A6CA12 | |
| SCHEMBL29425705 | 0.79 | FBP1 (0.56) | ALDH1A1NFE2L2FBP1TTRPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | ALDH1A1 1541/4885UNG 4784/4885NFE2L2 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.