Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.76 |
| ▸ | DDX3X | O00571 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | ESRRG | P62508 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778986 | 1.00 | NOX1 (0.76) | NOX1DDX3XRAB9AMAPTNPC1 | |
| SCHEMBL669782 | 0.80 | SMN1; SMN2 (0.67) | RAB9AMAPTNPC1HPGDSMN1; SMN2 | |
| SCHEMBL203519 | 0.79 | NOX1 (0.67) | NOX1DDX3XRAB9AMAPTNPC1 | |
| SCHEMBL203520 | 0.79 | NOX1 (0.67) | NOX1DDX3XRAB9AMAPTNPC1 | |
| SCHEMBL11746811 | 0.77 | NOX1 (0.63) | NOX1DDX3XRAB9AMAPTNPC1 | |
| Dimethylamine SCHEMBL5779577 | 0.76 | GAA (0.59) | NOX1RAB9AMAPTNPC1HPGD | |
| SCHEMBL14418822 | 0.76 | NOX1 (0.62) | NOX1RAB9AMAPTNPC1HPGD | |
| SCHEMBL12258490 | 0.75 | NOX1 (0.73) | NOX1DDX3XRAB9AMAPTNPC1 | |
| SCHEMBL5776498 | 0.75 | NOX1 (0.61) | NOX1DDX3XRAB9AMAPTNPC1 | |
| SCHEMBL5776502 | 0.75 | NOX1 (0.61) | NOX1DDX3XRAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | NOX1 1745/4885DDX3X 3003/4885RAB9A 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.