Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779089 | 1.00 | KEAP1 (0.49) | KEAP1NFE2L2HPGDACKR3NPC1 | |
| SCHEMBL5256945 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2HPGDACKR3GAA | |
| SCHEMBL5256943 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2HPGDACKR3GAA | |
| SCHEMBL10551035 | 0.84 | KEAP1 (0.40) | KEAP1NFE2L2HPGDACKR3GAA | |
| SCHEMBL5776553 | 0.83 | HPGD (0.54) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10575701 | 0.83 | HPGD (0.54) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10883759 | 0.82 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL10883764 | 0.82 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL9589970 | 0.81 | HPGD (0.40) | HPGDNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL9589976 | 0.81 | HPGD (0.40) | HPGDNPC1RAB9ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572657-A4 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORP (KR) | 2006-03-01 | — | — | EP | disclosed |
| EP-1572657-A1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | Yuhan Corporation (KR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056781-A1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORPORATION (KR) | 2004-07-08 | — | — | WO | disclosed |