Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10575701 | 1.00 | HPGD (0.54) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL10883759 | 0.93 | HPGD (0.46) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL10883764 | 0.93 | HPGD (0.46) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL10843040 | 0.87 | HPGD (0.40) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL9589970 | 0.87 | HPGD (0.40) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL9589976 | 0.87 | HPGD (0.40) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL10594984 | 0.86 | HPGD (0.50) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL9875263 | 0.86 | HPGD (0.50) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL9491280 | 0.86 | HPGD (0.50) | HPGDSMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL5779087 | 0.83 | KEAP1 (0.49) | HPGDSMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572657-A4 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORP (KR) | 2006-03-01 | — | — | EP | disclosed |
| EP-1572657-A1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | Yuhan Corporation (KR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056781-A1 | PROCESSES FOR PREPARING QUINOLONECARBOXYLATE DERIVATIVES | YUHAN CORPORATION (KR) | 2004-07-08 | — | — | WO | disclosed |
| US-4833270-A | Process for preparing 2-chloro-4,5-difluorobenzoic acid | AMERICAN CYANAMID COMPANY (US) | 1989-05-23 | — | — | US | disclosed |