Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.72 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.51 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.51 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | CTH | P32929 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779169 | 1.00 | MPO (0.72) | MPOAPPNPC1RAB9AKMT2A | |
| SCHEMBL2681678 | 0.83 | MPO (0.71) | MPONPC1RAB9AKMT2AMEN1 | |
| SCHEMBL6663830 | 0.83 | MPO (0.71) | MPONPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5779390 | 0.82 | NPC1 (0.64) | MPOAPPNPC1RAB9AKMT2A | |
| SCHEMBL5779393 | 0.82 | NPC1 (0.64) | MPOAPPNPC1RAB9AKMT2A | |
| SCHEMBL15810344 | 0.81 | MPO (0.68) | MPONPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5779576 | 0.80 | MPO (0.48) | MPONPC1RAB9AKMT2AMEN1 | |
| SCHEMBL5779571 | 0.80 | MPO (0.48) | MPONPC1RAB9AKMT2AMEN1 | |
| SCHEMBL22198277 | 0.79 | APP (0.68) | APPNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL26935013 | 0.79 | GAA (0.72) | MPONPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | MPO 2642/4885APP 1/4885NPC1 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.