Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.64 |
| ▸ | MPO | P05164 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.47 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.47 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779390 | 1.00 | NPC1 (0.64) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL5779169 | 0.82 | MPO (0.72) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL5779166 | 0.82 | MPO (0.72) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL6663830 | 0.82 | MPO (0.71) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL2681678 | 0.82 | MPO (0.71) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL12258152 | 0.79 | NPC1 (1.00) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL5775875 | 0.78 | RAB9A (0.68) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL22198258 | 0.76 | APP (0.69) | NPC1RAB9AKMT2AMEN1APP | |
| SCHEMBL12235651 | 0.71 | NPC1 (0.59) | NPC1RAB9AKMT2AGAAMEN1 | |
| SCHEMBL6565822 | 0.70 | RAB9A (0.62) | NPC1RAB9AKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | NPC1 952/4885RAB9A 3127/4885KMT2A 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.