Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.65 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319971 | 0.94 | EPHX1 (0.71) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| Dimethylamine SCHEMBL10414531 | 0.88 | EPHX1 (0.65) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL358575 | 0.86 | — | — | |
| SCHEMBL4577304 | 0.83 | EPHX1 (0.60) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL9323761 | 0.83 | EPHX1 (0.82) | EPHX1KDM4CMMP1MMP2EPHX2 | |
| SCHEMBL4577303 | 0.83 | EPHX1 (0.60) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL1416435 | 0.81 | EPHX1 (0.58) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL19881250 | 0.81 | EPHX1 (0.58) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL21582896 | 0.81 | EPHX1 (0.58) | EPHX1KDM4CMEN1KMT2AALDH1A1 | |
| SCHEMBL1753630 | 0.81 | EPHX1 (0.95) | EPHX1SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254904-B1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2006-05-24 | — | — | EP | disclosed |