SCHEMBL358575

SCHEMBL358575

CCCNC(=O)NCC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL319971 0.91 EPHX1 (0.71)
SCHEMBL23173031 0.88 EPHX1 (0.52)
Dimethylamine SCHEMBL10414531 0.86 EPHX1 (0.65)
SCHEMBL5779247 0.86 EPHX1 (0.65)
SCHEMBL28293734 0.85 MMP1 (0.48)
SCHEMBL320068 0.85
SCHEMBL969649 0.84 EPHX1 (0.74)
SCHEMBL13135023 0.83 EPHX1 (0.61)
SCHEMBL14198101 0.83 EPHX1 (0.68)
SCHEMBL1753987 0.82 EPHX1 (0.82)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone L'OREAL (FR) 2022-08-02 US claimed
US-11298305-B2 Compositions and methods for improving the appearance of the hair L'OREAL (FR) 2022-04-12 US claimed
CN-109641481-B Sulfur-crosslinkable rubber mixture and vehicle tire 赢创运营有限公司 2021-12-21 CN claimed
EP-3143081-B1 SULFUR-CROSSLINKABLE RUBBER MIXTURE AND VEHICLE TIRE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2021-12-08 EP claimed
US-10975231-B2 Sulfur-crosslinkable rubber mixture and vehicle tire EVONIK OPERATIONS GMBH (DE) 2021-04-13 US claimed
EP-2988830-B1 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF OREAL (FR) 2021-03-17 EP claimed
US-20190241721-A1 SULFUR-CROSSLINKABLE RUBBER MIXTURE AND VEHICLE TIRE EVONIK DEGUSSA GMBH (DE) 2019-08-08 US claimed
EP-2916808-B1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION OREAL (FR) 2019-06-26 EP claimed
US-20190167552-A1 COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR L'OREAL (FR) 2019-06-06 US claimed
US-20190117551-A1 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER L'OREAL (FR) 2019-04-25 US claimed
US-20160199276-A1 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF L'OREAL (FR) 2016-07-14 US claimed
US-20150305999-A1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION L'OREAL (FR) 2015-10-29 US claimed
EP-1661551-B1 Method of straightening keratin fibres with heating means and a denaturant agent ORÉAL L (FR) 2014-08-20 EP claimed
US-20100284954-A1 PROCESS FOR RELAXING KERATIN FIBRES L'OREAL (FR) 2010-11-11 US claimed
EP-2029095-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'Oréal (FR) 2009-03-04 EP claimed
WO-2007135297-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2007-11-29 WO claimed
US-20060127337-A1 Process for relaxing keratin fibres L'OREAL (FR) 2006-06-15 US claimed
EP-1661551-A2 Method of straightening keratin fibres with heating means and a denaturant agent L'OREAL (FR) 2006-05-31 EP claimed
US-20030139427-A1 Bicyclic pyrimidinyl derivatives and methods of use thereof OSI PHARMACEUTICALS INC. 2003-07-24 US claimed
US-4163797-A CARBAMOYL OR SULFAMOYL STABILIZER THE DOW CHEMICAL COMPANY (US) 1979-08-07 US claimed