⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL319971 | 0.91 | EPHX1 (0.71) | — | |
| SCHEMBL23173031 | 0.88 | EPHX1 (0.52) | — | |
| Dimethylamine SCHEMBL10414531 | 0.86 | EPHX1 (0.65) | — | |
| SCHEMBL5779247 | 0.86 | EPHX1 (0.65) | — | |
| SCHEMBL28293734 | 0.85 | MMP1 (0.48) | — | |
| SCHEMBL320068 | 0.85 | — | — | |
| SCHEMBL969649 | 0.84 | EPHX1 (0.74) | — | |
| SCHEMBL14198101 | 0.83 | EPHX1 (0.68) | — | |
| SCHEMBL13135023 | 0.83 | EPHX1 (0.61) | — | |
| SCHEMBL1753987 | 0.82 | EPHX1 (0.82) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | L'OREAL (FR) | 2022-08-02 | — | — | US | claimed |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | L'OREAL (FR) | 2022-04-12 | — | — | US | claimed |
| CN-109641481-B | Sulfur-crosslinkable rubber mixture and vehicle tire | 赢创运营有限公司 | 2021-12-21 | — | — | CN | claimed |
| EP-3143081-B1 | SULFUR-CROSSLINKABLE RUBBER MIXTURE AND VEHICLE TIRE | CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) | 2021-12-08 | — | — | EP | claimed |
| US-10975231-B2 | Sulfur-crosslinkable rubber mixture and vehicle tire | EVONIK OPERATIONS GMBH (DE) | 2021-04-13 | — | — | US | claimed |
| EP-2988830-B1 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | OREAL (FR) | 2021-03-17 | — | — | EP | claimed |
| US-20190241721-A1 | SULFUR-CROSSLINKABLE RUBBER MIXTURE AND VEHICLE TIRE | EVONIK DEGUSSA GMBH (DE) | 2019-08-08 | — | — | US | claimed |
| EP-2916808-B1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | OREAL (FR) | 2019-06-26 | — | — | EP | claimed |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2019-06-06 | — | — | US | claimed |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | L'OREAL (FR) | 2019-04-25 | — | — | US | claimed |
| US-20160199276-A1 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | L'OREAL (FR) | 2016-07-14 | — | — | US | claimed |
| US-20150305999-A1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | L'OREAL (FR) | 2015-10-29 | — | — | US | claimed |
| EP-1661551-B1 | Method of straightening keratin fibres with heating means and a denaturant agent | ORÉAL L (FR) | 2014-08-20 | — | — | EP | claimed |
| US-20100284954-A1 | PROCESS FOR RELAXING KERATIN FIBRES | L'OREAL (FR) | 2010-11-11 | — | — | US | claimed |
| EP-2029095-A2 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'Oréal (FR) | 2009-03-04 | — | — | EP | claimed |
| WO-2007135297-A2 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2007-11-29 | — | — | WO | claimed |
| US-20060127337-A1 | Process for relaxing keratin fibres | L'OREAL (FR) | 2006-06-15 | — | — | US | claimed |
| EP-1661551-A2 | Method of straightening keratin fibres with heating means and a denaturant agent | L'OREAL (FR) | 2006-05-31 | — | — | EP | claimed |
| US-20030139427-A1 | Bicyclic pyrimidinyl derivatives and methods of use thereof | OSI PHARMACEUTICALS INC. | 2003-07-24 | — | — | US | claimed |
| US-4163797-A | CARBAMOYL OR SULFAMOYL STABILIZER | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | claimed |