SCHEMBL319971

SCHEMBL319971

CCCNC(=O)NCCC

nearest known ligand 0.71

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 7/20 0.71
KDM4C Q9H3R0 1/20 0.56
MMP1 P03956 1/20 0.52
MMP2 P08253 1/20 0.52
MMP3 P08254 1/20 0.52
MMP9 P14780 1/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.48
EPHX2 P34913 1/20 0.48
MCL1 Q07820 1/20 0.48
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5779247 0.94 EPHX1 (0.65) EPHX1KDM4CMMP1MMP2MMP3
Dimethylamine SCHEMBL10414531 0.94 EPHX1 (0.65) EPHX1KDM4CMMP1MMP2MMP3
SCHEMBL358575 0.91
SCHEMBL4577304 0.89 EPHX1 (0.60) EPHX1KDM4CMMP1MMP2MMP3
SCHEMBL9323761 0.89 EPHX1 (0.82) EPHX1KDM4CMMP1MMP2EPHX2
SCHEMBL4577303 0.89 EPHX1 (0.60) EPHX1KDM4CMMP1MMP2MMP3
SCHEMBL1416435 0.87 EPHX1 (0.58) EPHX1KDM4CMMP1MMP2MMP3
SCHEMBL19881250 0.87 EPHX1 (0.58) EPHX1KDM4CMMP1MMP2MMP3
SCHEMBL21582896 0.87 EPHX1 (0.58) EPHX1KDM4CMMP1MMP2MMP3
SCHEMBL1753630 0.87 EPHX1 (0.95) EPHX1SMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116102466-B Preparation method of 1, 3-dipropylurea compound 沈阳化工大学 2024-08-09 CN claimed
CN-117621582-B Layered composite material and preparation method and application thereof 河北英利奥体育用品有限公司 2024-06-11 CN claimed
CN-117621582-A Layered composite material and preparation method and application thereof 河北英利奥体育用品有限公司 2024-03-01 CN claimed
CN-116102466-A Preparation method of dialkyl urea compound 沈阳化工大学 2023-05-12 CN claimed
US-20220256854-A1 PLANT TREATMENT COMPOSITION CRODA INTERNATIONAL PLC (GB) 2022-08-18 US claimed
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone L'OREAL (FR) 2022-08-02 US claimed
EP-3986135-A1 PLANT TREATMENT COMPOSITION Croda International PLC (GB) 2022-04-27 EP claimed
US-11298305-B2 Compositions and methods for improving the appearance of the hair L'OREAL (FR) 2022-04-12 US claimed
EP-2988830-B1 COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF OREAL (FR) 2021-03-17 EP claimed
EP-2916808-B1 COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION OREAL (FR) 2019-06-26 EP claimed
US-20080275209-A1 POLY(CARBONATE-CO-UREA) COPOLYMERS AND MELT TRANSESTERIFICATION METHOD OF PREPARING THESE COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-11-06 US claimed
EP-1716197-B1 HIGHLY FUNCTIONAL, HIGHLY BRANCHED POLYUREAS BASF SE (DE) 2008-10-29 EP claimed
US-20080030560-A1 Ink jet ink compositions for endorsing applications NU-KOTE INTERNATIONAL, INC. 2008-02-07 US claimed
WO-2007135297-A2 PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS L'OREAL (FR) 2007-11-29 WO claimed
US-20060127337-A1 Process for relaxing keratin fibres L'OREAL (FR) 2006-06-15 US claimed
EP-1661551-A2 Method of straightening keratin fibres with heating means and a denaturant agent L'OREAL (FR) 2006-05-31 EP claimed
WO-2006053033-A2 INK JET INK COMPOSITIONS FOR ENDORSING APPLICATIONS NU-KOTE INTERNATIONAL, INC. (US) 2006-05-18 WO claimed
US-6350795-B1 ACOUSTIC PHASE-CHANGE CONDUCTIVE INK CONTAINING LOW MOLECULAR WEIGHT OXYALKYLENE SEGMENTS COMPLEXED WITH UREA DERIVATIVES XEROX CORPORATION 2002-02-26 US claimed
US-5484457-A Continuous production of surface dyeings on cellulose fiber textile materials BASF AKTIENGESELLSCHAFT (DE) 1996-01-16 US claimed
US-4255572-A REACTING FORMIC ACID, PHOSPHORUS TRICHLORIDE, AND AN N,N'-DIALKYLUREA, WATER TREATMENT AGENTS KRUGER FRIEDRICH 1981-03-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11298305-B2 Compositions and methods for improving the appearance of the hair KRT18, OAT, CKMT1A; CKMT1B EPHX1 4323/4885KDM4C 504/4885MMP1 214/4885
US-20060127337-A1 Process for relaxing keratin fibres KRT18, TPM4, MYLK EPHX1 4336/4885KDM4C 219/4885MMP1 371/4885
US-11400042-B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone KRT18, CUTA, PUF60 EPHX1 4454/4885KDM4C 429/4885MMP1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.