Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780978 | 0.84 | MEN1 (0.42) | SIGMAR1ATMALDH1A1L3MBTL1 | |
| SCHEMBL5781065 | 0.83 | ACHE (0.39) | SIGMAR1ATMALDH1A1L3MBTL1ACHE | |
| SCHEMBL5781929 | 0.82 | CCR3 (0.38) | SIGMAR1ATMALDH1A1L3MBTL1 | |
| SCHEMBL5800740 | 0.80 | ATM (0.39) | SIGMAR1ATMALDH1A1ACHE | |
| SCHEMBL5778819 | 0.80 | SIGMAR1 (0.39) | SIGMAR1ATMALDH1A1L3MBTL1ACHE | |
| SCHEMBL5781370 | 0.80 | RECQL (0.38) | SIGMAR1ATMALDH1A1L3MBTL1ACHE | |
| SCHEMBL6888193 | 0.77 | SMN1; SMN2 (0.36) | SIGMAR1ALDH1A1L3MBTL1ACHE | |
| SCHEMBL5782582 | 0.77 | CYP2D6 (0.39) | SIGMAR1ALDH1A1L3MBTL1HRH3 | |
| SCHEMBL5778870 | 0.77 | ATM (0.61) | SIGMAR1ATMALDH1A1L3MBTL1 | |
| SCHEMBL5783601 | 0.75 | SLC6A2 (0.36) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254904-B1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2006-05-24 | — | — | EP | disclosed |
| US-6784192-B2 | NA+ CHANNEL INHIBITORY ACTION IS USEFUL FOR THERAPY AND PREVENTION FOR EXAMPLE, ARRHYTHMIA, VARIOUS NEURALGIAS AND ANALGESIC | EISAI CO., LTD. (JP) | 2004-08-31 | — | — | US | disclosed |
| US-20030220368-A1 | Novel piperidine compouds and drugs containing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220368-A1 | Novel piperidine compouds and drugs containing the same | TRPV1, CACNA1D, KCND2 | SIGMAR1 275/4885ATM 4830/4885ALDH1A1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.