SCHEMBL5367596

SCHEMBL5367596

NC(=O)N1CCC(N2CCCCC2)CC1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 16/20 0.58
L3MBTL1 Q9Y468 14/20 0.58
MBTD1 Q05BQ5 5/20 0.58
TP53BP1 Q12888 2/20 0.55
L3MBTL4 Q8NA19 1/20 0.55
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6108511 0.98 L3MBTL3 (0.56) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL920191 0.83 L3MBTL3 (0.61) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL6806463 0.83 L3MBTL3 (0.61) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL3155682 0.81 L3MBTL3 (0.59) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL3216528 0.81 POLB (0.55) L3MBTL3L3MBTL1MEN1KMT2AKDM4E
SCHEMBL920485 0.81 L3MBTL3 (0.59) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL27598275 0.80 L3MBTL3 (0.60) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL14899995 0.80 L3MBTL3 (0.50) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL1400926 0.80 L3MBTL3 (0.45) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4
SCHEMBL5779438 0.80 L3MBTL3 (0.55) L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023193789-A1 WEE1 DEGRADING COMPOUNDS BEIJING NEOX BIOTECH LIMITED (CN) 2023-10-12 WO claimed
CN-110105344-A A kind of compound and its synthetic method and application 北京大学 2019-08-09 CN claimed
US-20070208036-A1 Arylalkanes, arylalkenes and aryl-azaalkanes, pharmaceutical compositions containing these compounds and processes for preparing them BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-09-06 US claimed
US-7230001-B1 Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-06-12 US claimed
US-20020151501-A1 Compounds having growth hormone releasing activity BOWERS CYRIL Y (US) 2002-10-17 US claimed
EP-1159292-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY Administrators of The Tulane Educational Fund (US) 2001-12-05 EP claimed
WO-2000009537-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2000-02-24 WO claimed
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES Illudent, Inc. (US) 2025-09-25 US disclosed
US-20250241872-A1 AFFINITY MEDICANT CONJUGATE Illudent, Inc. (US) 2025-07-31 US disclosed
US-12280021-B2 Affinity medicant conjugate AF CHEMICALS, LLC (US) 2025-04-22 US disclosed
US-12269793-B2 Affinity illudofulvene conjugates AF CHEMICALS, LLC (US) 2025-04-08 US disclosed
CN-114728917-B Oxamide derivative, preparation method and medical application thereof 深圳信立泰药业股份有限公司 2023-12-08 CN disclosed
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE Califia Pharma Inc. (US) 2023-11-23 US disclosed
US-7250399-B2 Compounds having growth hormone releasing activity THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2007-07-31 US disclosed
US-7230001-B1 Arylalkane, arylalkene and aryl azaalkane, medicaments containing said compounds and method for the production thereof BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2007-06-12 US disclosed
US-6468974-B1 OLIGOPEPTIDES THAT PROVIDE DESIRABLE IN VITRO AND IN VIVO GROWTH HORMONE RELEASING ACTIVITY AND HAVE AT LEAST ONE OTHER DESIRABLE BIOLOGICAL ACTIVITY SUCH AS INCREASED RETENTION TIME THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND 2002-10-22 US disclosed
US-20020151501-A1 Compounds having growth hormone releasing activity BOWERS CYRIL Y (US) 2002-10-17 US disclosed
EP-1159292-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY Administrators of The Tulane Educational Fund (US) 2001-12-05 EP disclosed
WO-2001007409-A1 CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS ASTRAZENECA UK LIMITED (GB) 2001-02-01 WO disclosed
WO-2000009537-A2 COMPOUNDS HAVING GROWTH HORMONE RELEASING ACTIVITY ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250296912-A1 AFFINITY ILLUDOFULVENE CONJUGATES OGFR, TNFSF11, FCER2 L3MBTL3 723/4885L3MBTL1 449/4885MBTD1 1000/4885
US-12280021-B2 Affinity medicant conjugate FCER2, HDGF, FCGR2A L3MBTL3 2807/4885L3MBTL1 2023/4885MBTD1 916/4885
US-20070208036-A1 Arylalkanes, arylalkenes and aryl-azaalkanes, pharmaceutical compositions containing these compounds and processes for preparing them ARRB1, NPY1R, ADRB3 L3MBTL3 4672/4885L3MBTL1 4723/4885MBTD1 3453/4885
US-20230372267-A1 AFFINITY MEDICANT CONJUGATE FCER2, HDGF, FCGR2A L3MBTL3 2807/4885L3MBTL1 2023/4885MBTD1 916/4885
US-20020151501-A1 Compounds having growth hormone releasing activity GHSR, GHRHR, NPY1R L3MBTL3 3028/4885L3MBTL1 2502/4885MBTD1 2040/4885
US-12269793-B2 Affinity illudofulvene conjugates OGFR, TNFSF11, FCER2 L3MBTL3 723/4885L3MBTL1 449/4885MBTD1 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.