Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11810624 | 0.75 | CYP11B2 (0.35) | IRAK4PRKCZCYP11B1CYP11B2CNR1 | |
| SCHEMBL28442398 | 0.73 | TDP1 (0.41) | PRKCZCYP11B1CYP11B2CNR1CNR2 | |
| SCHEMBL13728399 | 0.72 | CYP11B2 (0.42) | IRAK4PRKCZCYP11B1CYP11B2CNR1 | |
| SCHEMBL7963921 | 0.72 | HTR2C (0.49) | IRAK4HTR1A | |
| SCHEMBL30735834 | 0.72 | HTR2C (0.49) | IRAK4HTR1A | |
| SCHEMBL11665783 | 0.71 | TDP1 (0.44) | PRKCZCYP11B1CYP11B2CNR1CNR2 | |
| Cyclohexane SCHEMBL22288135 | 0.71 | TDP1 (0.44) | PRKCZCYP11B1CYP11B2CNR1CNR2 | |
| SCHEMBL12676840 | 0.68 | PRKCZ (0.35) | IRAK4PRKCZCYP11B1CYP11B2CNR1 | |
| SCHEMBL4155227 | 0.67 | SLC18A3 (0.42) | ADRA1A | |
| SCHEMBL31596812 | 0.66 | MEN1 (0.40) | IRAK4PRKCZCYP11B1CYP11B2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |