Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5780456 | 0.95 | PTGDR2 (0.43) | MEN1KMT2APTGDR2RBP4MAPT | |
| SCHEMBL5777663 | 0.91 | CXCR4 (0.43) | MAPTCCR8KCNH2CXCR4DCPS | |
| Oxalic Acid SCHEMBL5778829 | 0.86 | MEN1 (0.46) | MEN1KMT2AMAPTCCR8KCNH2 | |
| SCHEMBL5784012 | 0.85 | MAPT (0.40) | MEN1KMT2AMAPTSLC6A2SLC6A4 | |
| SCHEMBL5780290 | 0.85 | KCNH2 (0.42) | MAPTKCNH2CXCR4DCPS | |
| SCHEMBL5781590 | 0.84 | KCNH2 (0.43) | MAPTKCNH2DCPSCYP2D6 | |
| SCHEMBL5778916 | 0.84 | DCPS (0.36) | MAPTCCR8KCNH2CXCR4DCPS | |
| SCHEMBL5779805 | 0.82 | HPGD (0.37) | MAPTCCR8KCNH2CXCR4DCPS | |
| SCHEMBL5782084 | 0.81 | DCPS (0.50) | MEN1KMT2AMAPTCXCR4DCPS | |
| SCHEMBL5779389 | 0.81 | DCPS (0.50) | MAPTDCPSCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1254904-B1 | NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME | EISAI CO LTD (JP) | 2006-05-24 | — | — | EP | claimed |