SCHEMBL5778916

SCHEMBL5778916

O=c1[nH]cccc1CN1CCC(C#Cc2ccccc2OCC2CCCCC2)CC1

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DCPS Q96C86 6/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.35
CCR8 P51685 1/20 0.35
KCNH2 Q12809 1/20 0.35
CXCR4 P61073 1/20 0.34
BRD4 O60885 1/20 0.33
CREBBP Q92793 1/20 0.33
XDH P47989 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL5781174 0.96 MEN1 (0.39) DCPSCYP2D6MAPTCCR8KCNH2
SCHEMBL5777663 0.86 CXCR4 (0.43) DCPSCYP2D6MAPTCCR8KCNH2
SCHEMBL5778913 0.85 GRM2 (0.39)
SCHEMBL5779854 0.84 MEN1 (0.45) DCPSCYP2D6MAPTCCR8KCNH2
Oxalic Acid SCHEMBL5778829 0.82 MEN1 (0.46) DCPSCYP2D6MAPTCCR8KCNH2
SCHEMBL5782834 0.81 DCPS (0.48) DCPS
SCHEMBL5784012 0.81 MAPT (0.40) DCPSCYP2D6MAPTCCR8KCNH2
SCHEMBL5780290 0.81 KCNH2 (0.42) DCPSMAPTKCNH2CXCR4
SCHEMBL5781590 0.80 KCNH2 (0.43) DCPSCYP2D6MAPTKCNH2
SCHEMBL5779805 0.80 HPGD (0.37) DCPSCYP2D6MAPTCCR8KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1254904-B1 NOVEL PIPERIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME EISAI CO LTD (JP) 2006-05-24 EP claimed