Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17800105 | 1.00 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TRPA1TRPM8ALOX5 | |
| SCHEMBL9441857 | 1.00 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TRPA1TRPM8ALOX5 | |
| SCHEMBL2252062 | 1.00 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1TRPA1TRPM8ALOX5 | |
| SCHEMBL8024177 | 0.97 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1TRPA1TRPM8 | |
| SCHEMBL4764671 | 0.94 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1TRPA1TRPM8 | |
| SCHEMBL27114563 | 0.88 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL14230816 | 0.87 | L3MBTL1 (0.39) | L3MBTL1TRPA1TRPM8 | |
| SCHEMBL7553320 | 0.87 | L3MBTL1 (0.39) | L3MBTL1TRPA1TRPM8 | |
| SCHEMBL11401966 | 0.87 | L3MBTL1 (0.39) | L3MBTL1TRPA1TRPM8 | |
| SCHEMBL9802737 | 0.86 | ALDH1A1 (0.44) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2006-12-28 | — | — | US | disclosed |
| EP-1627870-A1 | CYANOFLUOROPYRROLIDINE DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293297-A1 | Cyanofluoropyrrolidine derviative | DPP4, DPP3, NPY4R | ALDH1A1 3197/4885L3MBTL1 1208/4885TRPA1 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.