Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408659 | 0.92 | PRKCI (0.74) | PRKCIPRKCZ | |
| SCHEMBL5779511 | 0.88 | KDM4E (0.61) | PRKCI | |
| SCHEMBL5782433 | 0.86 | PRKCI (0.66) | PRKCIPRKCZ | |
| SCHEMBL8169588 | 0.86 | PRKCI (0.59) | PRKCIPRKCZ | |
| SCHEMBL14986469 | 0.85 | PRKCI (1.00) | PRKCIPRKCZ | |
| SCHEMBL5781203 | 0.84 | PRKCI (0.55) | PRKCI | |
| SCHEMBL5782107 | 0.83 | PRKCI (0.65) | PRKCI | |
| SCHEMBL8184514 | 0.83 | PTGS2 (0.58) | PRKCI | |
| SCHEMBL5780827 | 0.83 | PRKCI (0.62) | PRKCIPRKCZ | |
| SCHEMBL7408485 | 0.83 | PRKCI (0.62) | PRKCIPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685136-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047292-A1 | USE OF THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 2005-05-26 | — | — | WO | disclosed |
| US-6110920-A | TREATMENT OF CARDIOVASCULAR DISORDERS AND IMPOTENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-08-29 | — | — | US | disclosed |