Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5780827 | 0.94 | PRKCI (0.62) | PRKCIPRKCZ | |
| SCHEMBL5780867 | 0.91 | PRKCI (0.66) | PRKCIPRKCZ | |
| SCHEMBL5776031 | 0.89 | MAPT (0.61) | PRKCIPRKCZ | |
| SCHEMBL7015745 | 0.88 | PTGS2 (0.53) | PRKCIPRKCZ | |
| SCHEMBL6709545 | 0.87 | PTGS2 (0.52) | PRKCIPRKCZ | |
| SCHEMBL5779717 | 0.86 | PRKCI (0.46) | PRKCI | |
| SCHEMBL5798171 | 0.85 | MEN1 (0.46) | PRKCI | |
| SCHEMBL8178899 | 0.85 | PTPN12 (0.49) | PRKCI | |
| SCHEMBL7172530 | 0.85 | MAPT (0.56) | PRKCIPRKCZ | |
| SCHEMBL5778467 | 0.85 | MEN1 (0.52) | PRKCIPRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110920-A | TREATMENT OF CARDIOVASCULAR DISORDERS AND IMPOTENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-08-29 | — | — | US | disclosed |
| EP-0920431-A1 | THIENOPYRIMIDINES | MERCK PATENT GmbH (DE) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998006722-A1 | THIENOPYRIMIDINES | MERCK PATENT GMBH (DE) | 1998-02-19 | — | — | WO | disclosed |