SCHEMBL578007

SCHEMBL578007

O=P(O)(O)Cc1cc(F)c(F)c(F)c1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 10/20 0.54
PGK2 P07205 10/20 0.54
PTPRB P23467 2/20 0.48
ACP3 P15309 1/20 0.43
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12606478 0.86 PGK1 (0.55) PGK1PGK2PTPRBACP3
SCHEMBL8824567 0.80 PGK1 (0.76) PGK1PGK2PTPRBACP3
SCHEMBL578288 0.79 PGK1 (0.56) PGK1PGK2PTPRBACP3GRIN2D
SCHEMBL9277395 0.74 ACP3 (0.45) PGK1PGK2ACP3
SCHEMBL31091012 0.72 MAOB (0.46) CES2CES1
SCHEMBL2636963 0.72 PGK1 (0.43) PGK1PGK2PTPRB
SCHEMBL26544979 0.71 PGK1 (0.64) PGK1PGK2PTPRBACP3
SCHEMBL12606471 0.71 PGK1 (0.74) PGK1PGK2PTPRBACP3GRIN2D
SCHEMBL6154389 0.70 TRPV4 (0.49) PGK1PGK2ACP3
SCHEMBL22973707 0.70 PGK1 (0.61) PGK1PGK2PTPRBACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102459290-B Electronic devices comprising novel phosphonic acid surface modifiers 乔治亚州技术研究公司 2017-03-22 CN disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
CN-104641471-A Coating material for oxide thin film transistor POLYERA CORP 2015-05-20 CN disclosed
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-20140021465-A1 Coating Materials for Oxide Thin Film Transistors FLEXTERRA, INC. 2014-01-23 US disclosed
US-20140021465-A1 Coating Materials for Oxide Thin Film Transistors FLEXTERRA, INC. 2014-01-23 US disclosed
EP-2417142-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS Georgia Tech Research Corporation (US) 2012-02-15 EP disclosed
CN-102099941-A Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RES INST 2011-06-15 CN disclosed
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2011-05-19 US disclosed
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2011-05-19 US disclosed
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2011-05-19 US disclosed
EP-2304820-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES Georgia Tech Research Corporation (US) 2011-04-06 EP disclosed
WO-2010115854-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS GEORGIA TECH RESEARCH CORPORATION (US) 2010-10-14 WO disclosed
WO-2010115854-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS GEORGIA TECH RESEARCH CORPORATION (US) 2010-10-14 WO disclosed
WO-2010007081-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2010-01-21 WO disclosed
WO-2010007081-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2010-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices EPCAM, EMD, L1CAM PGK1 3140/4885PGK2 3522/4885PTPRB 727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.