Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5778720 | 0.91 | KDM4E (0.41) | THRBHPGDKDM4EMDM2HSD17B10 | |
| SCHEMBL5779114 | 0.90 | THRB (0.47) | THRBHPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL5781185 | 0.89 | THRB (0.48) | THRBHPGDHSD17B10KMT2APTGER4 | |
| SCHEMBL5783864 | 0.88 | THRB (0.46) | THRBHPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL5783447 | 0.88 | HPGD (0.46) | THRBHPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL4703168 | 0.87 | THRB (0.48) | THRBHPGDHSD17B10KMT2APTGER4 | |
| SCHEMBL4702408 | 0.87 | THRB (0.44) | THRBHPGDHSD17B10KMT2APTGER4 | |
| SCHEMBL5783074 | 0.86 | THRB (0.45) | THRBHPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL5777910 | 0.85 | THRB (0.43) | THRBHPGDHSD17B10KMT2AALDH1A1 | |
| SCHEMBL5780735 | 0.85 | THRB (0.43) | THRBHPGDHSD17B10KMT2APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194410-B1 | BENZIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THESE COMPOUNDS | NEUROSEARCH AS (DK) | 2006-01-18 | — | — | EP | claimed |