Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781061 | 0.83 | GSK3B (0.42) | POLBKMT2AUTS2RFLT1FLT4 | |
| SCHEMBL5781059 | 0.83 | GSK3B (0.42) | POLBKMT2AUTS2RFLT1FLT4 | |
| SCHEMBL5781380 | 0.82 | CES2 (0.43) | TDP1KMT2AMAPTMEN1LMNA | |
| SCHEMBL31359583 | 0.82 | CES2 (0.43) | TDP1KMT2AMAPTMEN1LMNA | |
| SCHEMBL5781385 | 0.82 | CES2 (0.43) | TDP1KMT2AMAPTMEN1LMNA | |
| SCHEMBL5885253 | 0.80 | FLT1 (0.43) | POLBKMT2AUTS2RFLT1FLT4 | |
| SCHEMBL27539032 | 0.80 | PTGDR2 (0.34) | TDP1KMT2AMEN1LMNATSHR | |
| SCHEMBL1922661 | 0.78 | FLT1 (0.42) | POLBKMT2AUTS2RFLT1FLT4 | |
| SCHEMBL117133 | 0.77 | MAPT (0.49) | KMT2AFLT1FLT4KDRMAPT | |
| SCHEMBL29420640 | 0.77 | MAPT (0.49) | KMT2AFLT1FLT4KDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397353-B1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | DOW AGROSCIENCES LLC (US) | 2006-10-25 | — | — | EP | disclosed |
| EP-1397353-A1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | Dow Agrosciences LLC (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6573286-B1 | Oxazoline compounds having a 2,6-disubstituted-phenyl group in the 2-position, an aryl or heteroaryl group in the 4-position and an alkyl group in the 5-position are effective in controlling aphids, insects and mites. | DOW AGROSCIENCES LLC | 2003-06-03 | — | — | US | disclosed |
| WO-2003000669-A1 | 2-(2,6-DISUBSTITUTED PHENYL)-4-ARYL-5-ALKYL-1,3-OXAZOLINE COMPOUNDS USEFUL AS INSECTICIDES AND ACARICIDES | DOW AGROSCIENCES LLC (US) | 2003-01-03 | — | — | WO | disclosed |