Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.40 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.40 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781380 | 1.00 | CES2 (0.43) | CES2CES1LMNAKDM4EHTT | |
| SCHEMBL5781385 | 1.00 | CES2 (0.43) | CES2CES1LMNAKDM4EHTT | |
| SCHEMBL28910868 | 0.84 | CES2 (0.42) | CES2CES1LMNAKDM4EHTT | |
| SCHEMBL28910869 | 0.84 | CES2 (0.42) | CES2CES1LMNAKDM4EHTT | |
| SCHEMBL10711439 | 0.83 | TDP1 (0.54) | CES2CES1LMNAALDH1A1CYP3A4 | |
| SCHEMBL5780893 | 0.82 | POLB (0.42) | LMNAHTTRAB9AMEN1KMT2A | |
| SCHEMBL14297444 | 0.81 | ALDH1A1 (0.46) | CES2CES1LMNAALDH1A1CYP3A4 | |
| SCHEMBL5761398 | 0.81 | GSK3B (0.50) | LMNAALDH1A1CYP3A4RAB9AMEN1 | |
| SCHEMBL3446600 | 0.81 | ALDH1A1 (0.62) | LMNAKDM4EALDH1A1CYP3A4RAB9A | |
| SCHEMBL8864141 | 0.81 | MEN1 (0.48) | CES2CES1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119263946-A | Preparation method of alpha-acyloxyketone compound | 华南师范大学 | 2025-01-07 | — | — | CN | disclosed |