Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PRKCA | P17252 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5785627 | 0.92 | ITGB3 (0.39) | ITGB3ITGA2BKDM4EPKMALDH1A1 | |
| SCHEMBL5785086 | 0.89 | ITGB3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL5785030 | 0.84 | ITGB3 (0.37) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL5782934 | 0.82 | ITGB3 (0.39) | ITGB3ITGA2BALDH1A1 | |
| SCHEMBL5783539 | 0.79 | ITGB3 (0.33) | ITGB3ITGA2BKDM4E | |
| SCHEMBL5783451 | 0.77 | TPSAB1 (0.37) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL5784542 | 0.75 | HPGD (0.39) | KDM4EALDH1A1GAA | |
| SCHEMBL5784707 | 0.74 | HPGD (0.38) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL5782451 | 0.74 | HPGD (0.46) | KDM4EALDH1A1GAA | |
| SCHEMBL5781784 | 0.73 | GAA (0.35) | KDM4EPKMALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |