Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MPL | P40238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12637455 | 0.83 | CYP3A4 (0.39) | WDR5ALDH1A1HSD17B10MPL | |
| SCHEMBL15465950 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10MPL | |
| SCHEMBL6669333 | 0.72 | HSD11B1 (0.42) | ALDH1A1HSD17B10 | |
| SCHEMBL5785066 | 0.72 | ALOX5AP (0.39) | WDR5ALDH1A1HSD17B10 | |
| SCHEMBL1880384 | 0.70 | NAMPT (0.46) | NAMPTALDH1A1HSD17B10 | |
| SCHEMBL547334 | 0.69 | KDM4E (0.38) | ALDH1A1HSD17B10 | |
| SCHEMBL5672607 | 0.69 | HSD11B1 (0.46) | MPL | |
| SCHEMBL12637498 | 0.69 | NAMPT (0.33) | NAMPTALDH1A1HSD17B10 | |
| SCHEMBL12637494 | 0.67 | NAMPT (0.32) | NAMPTALDH1A1HSD17B10 | |
| SCHEMBL10616457 | 0.66 | ALDH1A1 (0.40) | NAMPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670794-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | Amgen Inc. (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005033105-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2005-04-14 | — | — | WO | disclosed |