Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.33 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.33 |
| ▸ | PRKCB | P05771 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5585680 | 0.80 | HTR2C (0.45) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585944 | 0.80 | HTR2C (0.45) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585677 | 0.80 | HTR2C (0.45) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| Acetic Acid SCHEMBL6183906 | 0.75 | PRKCQ (0.41) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585951 | 0.75 | HTR6 (0.40) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585948 | 0.75 | HTR6 (0.40) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585785 | 0.72 | ADRB2 (0.65) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585596 | 0.72 | ADRB2 (0.65) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5585598 | 0.72 | ADRB2 (0.65) | HTR2CADRB2PRKCQPRKCDPRKCB | |
| SCHEMBL5780913 | 0.72 | HTR2C (0.41) | HTR2CADRB2PRKCQPRKCDPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506185-B1 | COMPOUNDS AND THEIR USE AS INHIBITORS OF 5-HT | BIOVITRUM AB (SE) | 2006-05-24 | — | — | EP | disclosed |