Aminomethylbenzoic Acid

Aminomethylbenzoic Acid

SCHEMBL5781145

NCc1ccc(C(=O)O)cc1.Nc1ccc(C(=O)O)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 5/20 0.62
ALDH1A1 P00352 3/20 0.52
HDAC3 O15379 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
NCOR2 Q9Y618 1/20 0.52
TSHR P16473 2/20 0.50
TP53 P04637 1/20 0.50
F10 P00742 1/20 0.47
ANPEP P15144 1/20 0.46
ENPEP Q07075 1/20 0.46
SRD5A2 P31213 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
HIF1A Q16665 2/20 0.44
KMT2A Q03164 2/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminobenzoic Acid SCHEMBL16950263 1.00 LOXL2 (0.62) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminobenzoic Acid SCHEMBL8000099 0.92 TSHR (0.55) LOXL2TSHRTP53SRD5A2CYP1A2
Aminomethylbenzoic Acid SCHEMBL38758 0.91 ALDH1A1 (0.60) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL9344424 0.91 ALDH1A1 (0.60) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL7428232 0.89 ALDH1A1 (0.58) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL28342619 0.89 ALDH1A1 (0.58) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL1206230 0.89 ALDH1A1 (0.58) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL1567841 0.89 ALDH1A1 (0.58) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL11755138 0.87 ALDH1A1 (0.61) LOXL2ALDH1A1HDAC3HDAC6NCOR2
Aminomethylbenzoic Acid SCHEMBL8000841 0.86 ALDH1A1 (0.50) LOXL2ALDH1A1HDAC3HDAC6NCOR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1654005-A2 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR PREPARATION BRACCO IMAGING S.p.A. (IT) 2006-05-10 EP disclosed
WO-2005009393-A2 STABLE RADIOPHARMACEUTICAL COMPOSITIONS AND METHODS FOR PREPARATION BRACCO IMAGING S.P.A. (IT) 2005-02-03 WO disclosed