Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.54 |
| ▸ | CDK9 | P50750 | 2/20 | 0.54 |
| ▸ | ABL1 | P00519 | 7/20 | 0.53 |
| ▸ | BCR | P11274 | 6/20 | 0.53 |
| ▸ | PRKCA | P17252 | 3/20 | 0.53 |
| ▸ | SRC | P12931 | 4/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | PRKCG | P05129 | 1/20 | 0.52 |
| ▸ | PRKCB | P05771 | 1/20 | 0.52 |
| ▸ | PRKCH | P24723 | 1/20 | 0.52 |
| ▸ | PRKCI | P41743 | 1/20 | 0.52 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.52 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781477 | 0.92 | EGFR (0.57) | CCNT1CDK9ABL1BCRPRKCA | |
| SCHEMBL5782012 | 0.91 | ABL1 (0.63) | CCNT1CDK9ABL1BCRPRKCA | |
| SCHEMBL5780635 | 0.84 | KCNH2 (0.57) | CCNT1CDK9ABL1PRKCAPRKCD | |
| SCHEMBL5781152 | 0.83 | CDK4 (0.59) | CCNT1CDK9ABL1BCRSRC | |
| SCHEMBL5779741 | 0.83 | CCNT1 (0.53) | CCNT1CDK9ABL1BCRPRKCA | |
| SCHEMBL5780393 | 0.83 | CAMK2D (0.62) | CCNT1CDK9ABL1BCRPRKCA | |
| SCHEMBL5780335 | 0.83 | CCNT1 (0.51) | CCNT1CDK9ABL1BCRSRC | |
| SCHEMBL5779921 | 0.83 | CCNT1 (0.51) | CCNT1CDK9ABL1BCRSRC | |
| SCHEMBL5781821 | 0.82 | PIK3CG (0.60) | CCNT1CDK9ABL1PRKD3PRKCG | |
| SCHEMBL5778418 | 0.82 | CCNT1 (0.51) | CCNT1CDK9ABL1BCRPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1434776-B1 | THIAZOLYL SUBSTITUTED AMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-28 | — | — | EP | claimed |