Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
| ▸ | CDK4 | P11802 | 5/20 | 0.48 |
| ▸ | CDK2 | P24941 | 5/20 | 0.48 |
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.48 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | ABL2 | P42684 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CCNH | P51946 | 1/20 | 0.48 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611119 | 0.92 | CCNT1 (0.49) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL5781100 | 0.88 | CCNT1 (0.49) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL5779883 | 0.87 | CCNT1 (0.49) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL5780635 | 0.86 | KCNH2 (0.57) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL5780393 | 0.85 | CAMK2D (0.62) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL5779741 | 0.85 | CCNT1 (0.53) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL5781152 | 0.85 | CDK4 (0.59) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL6609023 | 0.84 | EGFR (0.55) | CCNT1CDK9CDK4CDK2ABL1 | |
| SCHEMBL12948400 | 0.83 | PIK3CG (0.61) | ABL1GSK3BEGFRMAPK8PIK3CG | |
| SCHEMBL5779921 | 0.82 | CCNT1 (0.51) | CCNT1CDK9CDK4CDK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105517-B2 | Thiazolyl substituted aminopyrimidines as plant protection agents | SYNGENTA CROP PROTECTION, INC. (US) | 2006-09-12 | — | — | US | disclosed |
| EP-1434776-B1 | THIAZOLYL SUBSTITUTED AMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2006-06-28 | — | — | EP | disclosed |
| US-20050038059-A1 | Thiazolyl substituted aminopyrimidines as plant protection agents | SYNGENTA CROP PROTECTION, INC. | 2005-02-17 | — | — | US | disclosed |
| EP-1434776-A1 | THIAZOLYL SUBSTITUTED AMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | Syngenta Participations AG (CH) | 2004-07-07 | — | — | EP | disclosed |
| WO-2003029249-A1 | THIAZOLYL SUBSTITUTED AMINOPYRIMIDINES AS PLANT PROTECTION AGENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2003-04-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038059-A1 | Thiazolyl substituted aminopyrimidines as plant protection agents | RARS2, CYP4X1, QDPR | CCNT1 653/4885CDK9 1570/4885CDK4 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.