SCHEMBL57818

SCHEMBL57818

Cc1ccc(C(=O)OC(C(=O)O)C(OC(=O)c2ccc(C)cc2)C(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.68
TSHR P16473 1/20 0.68
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PKM P14618 1/20 0.49
APEX1 P27695 1/20 0.49
CYP2C19 P33261 1/20 0.49
BLM P54132 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RECQL P46063 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
CYP2D6 P10635 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
LMNA P02545 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72171 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL938198 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL29777001 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL6532887 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL6309997 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL72682 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL883098 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL19279013 0.98 TP53 (0.66) TP53TSHRTDP1ALDH1A1SMN1; SMN2
Water SCHEMBL1322822 0.98 TP53 (0.66) TP53TSHRTDP1ALDH1A1SMN1; SMN2
Water SCHEMBL743190 0.98 TP53 (0.66) TP53TSHRTDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7240 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714955-A1 VERSATILE INTERMEDIATE FOR OPIOID DERIVATIVES, AND PREPARATION METHOD THEREFOR AND USE THEREOF Shaoxing Zejun Pharmaceuticals Co., Ltd (CN) 2026-03-25 EP claimed
US-12441745-B2 Processes and compounds RADIUS PHARMACEUTICALS, INC. (US) 2025-10-14 US claimed
CN-119954778-A Synthesis method of lenacipam sodium and series of intermediate compounds thereof 杭州科巢生物科技有限公司 2025-05-09 CN claimed
CN-119569588-A Preparation method and intermediate of ilast hydrochloride 杭州诺澳生物医药科技有限公司 2025-03-07 CN claimed
CN-119409612-A Resolution refining method of clemastine fumarate 南京斯泰尔医药科技有限公司 2025-02-11 CN claimed
CN-113348163-B Methods and compounds 雷迪厄斯制药公司 2024-10-08 CN claimed
WO-2024130425-A1 METHODS OF MAKING 2-AMINO-L-(3-HYDROXY-2,6-DIMETHYLPHENYL)-5,6- DIMETHYL-LH-PYRROLO-[2,3-B]PYRIDINE-3-CARBOXAMIDE, A MYTL INHIBITOR REPARE THERAPEUTICS INC. (CA) 2024-06-27 WO claimed
US-20240208903-A1 ACID ADDITION SALTS OF (S)-3-(2,5-DIMETHOXY-4-(TRIFLUOROMETHYL)PHENYL)PIPERIDINE AND (S)-3-(2-METHOXY-5-(METHYLTHIO)-4-(TRIFLUOROMETHYL)PHENYL)PIPERIDINE, SPECIFIC POLYMORPHS THEREOF AND METHODS FOR THEIR MANUFACTURE Lophora ApS (DK) 2024-06-27 US claimed
CN-118165070-A Salt and crystal form of 3CL protease small molecule inhibitor, and preparation methods and applications thereof 北京华益健康药物研究中心 2024-06-11 CN claimed
US-11999741-B2 Process for the synthesis of 6-((3S,4S)-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl)-3-(tetrahydropyran-4-yl-7H-imidazo[1,5-a]pyrazin-8-one CARDURION PHARMACEUTICALS, INC. (US) 2024-06-04 US claimed
EP-0575482-A1 ANTIVIRAL ACTIVITY AND RESOLUTION OF 2-HYDROXYMETHYL-5-(5-FLUOROCYTOSIN-1-YL)-1,3-OXATHIOLANE EMORY UNIVERSITY (US) 1993-12-29 EP claimed
EP-0539460-A1 SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II B. RHONE POULENC RORER SA (FR) 1993-05-05 EP claimed
WO-1992014743-A2 ANTIVIRAL ACTIVITY AND RESOLUTION OF 2-HYDROXYMETHYL-5-(5-FLUOROCYTOSIN-1-YL)-1,3-OXATHIOLANE EMORY UNIVERSITY (US) 1992-09-03 WO claimed
WO-1992001694-A1 NEW SALTS DERIVED FROM DIALKYLAMINOALKYLSULPHONYL-26 PRISTINAMYCIN II¿B? RHONE-POULENC RORER S.A. (FR) 1992-02-06 WO claimed
US-4931557-A Method of resolving cis 3-amino-4-(2-furyl)vinyl)-1-methoxycarbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof ELI LILLY AND COMPANY (US) 1990-06-05 US claimed
EP-0365213-A2 Method of resolving cis 3-amino-4-[2-(2-furyl)vinyl]-1-methoxy-carbonylmethyl-azetidin-2-one and di-p-toluoyl-tartaric acid salts thereof ELI LILLY AND COMPANY (US) 1990-04-25 EP claimed
EP-0251904-B1 PROCESS FOR THE PREPARATION OF ACIDIC LEVOMEPROMAZINE MALEATE RHONE-POULENC SANTE (FR) 1990-01-10 EP claimed
US-4798895-A Process for preparing levomepromazine hydrogen maleate RHONE-POULENC SANTE (FR) 1989-01-17 US claimed
US-4471121-A Method of resolving trans-d alpha-1-n-propyl-6-oxodecahydroquinoline and di-p-toluoyltartaric acid salts thereof ELI LILLY AND COMPANY (US) 1984-09-11 US claimed
EP-0112604-A1 Novel resolved keto compounds and process ELI LILLY AND COMPANY (US) 1984-07-04 EP claimed