Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938198 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL57818 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29777001 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6532887 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6309997 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL72682 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL883098 | 1.00 | TP53 (0.68) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL19279013 | 0.98 | TP53 (0.66) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| Water SCHEMBL1322822 | 0.98 | TP53 (0.66) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 | |
| Water SCHEMBL743190 | 0.98 | TP53 (0.66) | TP53TSHRTDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5394 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122010884-A | Preparation method of tetrahydronaphtho [1,2-b ] furan-2 (3H) -ketone compound | 江西普正制药股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20250276974-A1 | PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM | OLON S.P.A. (IT) | 2025-09-04 | — | — | US | claimed |
| WO-2025133917-A1 | PROCESS FOR THE PREPARATION OF (4S)-4-(4-CYANO-2-METHOXYPHENYL)-5- ETHOXY-1, 4-DIHYDRO-2,8-DIMETHYL-1,6-NAPTHYRIDINE-3-CARBOXAMIDE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2025-06-26 | — | — | WO | claimed |
| US-20250115601-A1 | PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF | ALIVUS LIFE SCIENCES LIMITED (IN) | 2025-04-10 | — | — | US | claimed |
| EP-4526302-A1 | PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF | Alivus Life Sciences Limited (IN) | 2025-03-26 | — | — | EP | claimed |
| EP-4522619-A1 | PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM | OLON S.p.A. (IT) | 2025-03-19 | — | — | EP | claimed |
| EP-4509183-A2 | CRYSTALLINE FORM OF (S)-7-(1-ACRYLOYLPIPERIDIN-4-YL)-2-(4-PHENOXYPHENYL)-4,5,6,7-TETRA-HYDROPYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE, PREPARATION, AND USES THEREOF | BeiGene Switzerland GmbH (CH) | 2025-02-19 | — | — | EP | claimed |
| CN-119462489-A | Method for obtaining (S) -chlorpheniramine through chiral resolution of chlorpheniramine | 中国药科大学 | 2025-02-18 | — | — | CN | claimed |
| CN-115974793-B | Racemization recovery method for resolution byproducts of letrozole intermediate | 浙江车头制药股份有限公司 | 2025-01-28 | — | — | CN | claimed |
| EP-4479546-A2 | PROCESSES FOR PREPARATION OF AVACOPAN AND INTERMEDIATES THEREOF | Teva Pharmaceuticals International GmbH (CH) | 2024-12-25 | — | — | EP | claimed |
| US-5399765-A | Salt formation | SEPRACOR, INC. (US) | 1995-03-21 | — | — | US | claimed |
| US-5387695-A | Precipitating one of the enantiomers in the form of the salt of a chiral acid | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1995-02-07 | — | — | US | claimed |
| EP-0420120-B1 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL (JP) | 1994-08-31 | — | — | EP | claimed |
| EP-0487237-A1 | New optically active metoprolol tartrate salts, and method of preparing them, and method of preparing optically active metoprolol from the tartrate salts | Nitto Denko Co. Ltd. (JP) | 1992-05-27 | — | — | EP | claimed |
| EP-0456196-A1 | Pyrrolo,[2,3-b]indole-ketones and analogs, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-11-13 | — | — | EP | claimed |
| EP-0438796-A2 | Process for the enantioselection synthesis of alkylated oxindoles used as intermediates in the preparation of physostigmine | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-07-31 | — | — | EP | claimed |
| EP-0420120-A2 | Optically active benzyl alcohol compound and pharmaceutical composition | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0418770-A2 | Process for the chemical resolution of 5-alkoxy-substituted (+/-)-1,3-dimethyloxindolylethylamines | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-03-27 | — | — | EP | claimed |
| EP-0251904-B1 | PROCESS FOR THE PREPARATION OF ACIDIC LEVOMEPROMAZINE MALEATE | RHONE-POULENC SANTE (FR) | 1990-01-10 | — | — | EP | claimed |
| US-4798895-A | Process for preparing levomepromazine hydrogen maleate | RHONE-POULENC SANTE (FR) | 1989-01-17 | — | — | US | claimed |