SCHEMBL72682

SCHEMBL72682

Cc1ccc(C(=O)O[C@H](C(=O)O)[C@H](OC(=O)c2ccc(C)cc2)C(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.68
TSHR P16473 1/20 0.68
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 3/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PKM P14618 1/20 0.49
APEX1 P27695 1/20 0.49
CYP2C19 P33261 1/20 0.49
BLM P54132 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RECQL P46063 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
CYP2D6 P10635 1/20 0.47
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
LMNA P02545 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72171 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL938198 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL57818 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL29777001 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL6532887 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL6309997 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
SCHEMBL883098 1.00 TP53 (0.68) TP53TSHRTDP1ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL19279013 0.98 TP53 (0.66) TP53TSHRTDP1ALDH1A1SMN1; SMN2
Water SCHEMBL1322822 0.98 TP53 (0.66) TP53TSHRTDP1ALDH1A1SMN1; SMN2
Water SCHEMBL743190 0.98 TP53 (0.66) TP53TSHRTDP1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5425 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722214-A1 METHOD OF PREPARING FINERENONE, INTERMEDIATE COMPOUND OF FINERENONE, AND METHOD OF PREPARING THE INTERMEDIATE COMPOUND JW Pharmaceutical Corporation (KR) 2026-04-08 EP claimed
EP-4642776-A1 SALTS AND SOLID FORMS OF SONROTOCLAX INTERMEDIATE Beone Medicines I GmbH (CH) 2025-11-05 EP claimed
US-20250276974-A1 PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM OLON S.P.A. (IT) 2025-09-04 US claimed
US-20250270184-A1 PROCESSES FOR THE PREPARATION OF FINERENONE ASSIA CHEMICAL INDUSTRIES LTD. (IL) 2025-08-28 US claimed
EP-4606429-A2 VMAT2 INHIBITORS AND METHODS OF USE Neurocrine Biosciences, Inc. (US) 2025-08-27 EP claimed
WO-2025133917-A1 PROCESS FOR THE PREPARATION OF (4S)-4-(4-CYANO-2-METHOXYPHENYL)-5- ETHOXY-1, 4-DIHYDRO-2,8-DIMETHYL-1,6-NAPTHYRIDINE-3-CARBOXAMIDE INDUSTRIALE CHIMICA S.R.L. (IT) 2025-06-26 WO claimed
US-20250136605-A1 IMPROVED METHODS FOR PREPARING CYTOTOXIC BENZODIAZEPINE DERIVATIVES IMMUNOGEN, INC. 2025-05-01 US claimed
US-20250115601-A1 PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF ALIVUS LIFE SCIENCES LIMITED (IN) 2025-04-10 US claimed
EP-4526302-A1 PROCESS FOR THE PREPARATION OF FINERENONE AND INTERMEDIATES THEREOF Alivus Life Sciences Limited (IN) 2025-03-26 EP claimed
EP-4522619-A1 PROCESS FOR PREPARING ZANUBRUTINIB IN AMORPHOUS FORM OLON S.p.A. (IT) 2025-03-19 EP claimed
EP-0420120-B1 Optically active benzyl alcohol compound and pharmaceutical composition HOKURIKU PHARMACEUTICAL (JP) 1994-08-31 EP claimed
US-5274117-A Heating a racemic oxindole, a halogenated acetonitrile and a catalyst to form the alkylated oxindole HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1993-12-28 US claimed
EP-0501774-A1 Preparation of substituted tetrahydropyridines ELI LILLY AND COMPANY (US) 1992-09-02 EP claimed
EP-0487237-A1 New optically active metoprolol tartrate salts, and method of preparing them, and method of preparing optically active metoprolol from the tartrate salts Nitto Denko Co. Ltd. (JP) 1992-05-27 EP claimed
EP-0472325-A2 Acid addition salts of an optically active alaninanilide compound and pharmaceutical compositions containing the same Kissei Pharmaceutical Co., Ltd. (JP) 1992-02-26 EP claimed
EP-0438796-A2 Process for the enantioselection synthesis of alkylated oxindoles used as intermediates in the preparation of physostigmine HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-07-31 EP claimed
EP-0420120-A2 Optically active benzyl alcohol compound and pharmaceutical composition HOKURIKU PHARMACEUTICAL CO., LTD. (JP) 1991-04-03 EP claimed
EP-0418770-A2 Process for the chemical resolution of 5-alkoxy-substituted (+/-)-1,3-dimethyloxindolylethylamines HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-03-27 EP claimed
US-4353918-A ANTIINFLAMMATORY, ANTIRHEUMATIC CIBA-GEIGY CORPORATION (US) 1982-10-12 US claimed
US-4329469-A SUSPENSION, SALT FORMATION MERCK & CO., INC. (US) 1982-05-11 US claimed