Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22610105 | 0.78 | GRM5 (0.35) | GRM5 | |
| SCHEMBL6858302 | 0.72 | GRM5 (0.36) | GRM5 | |
| SCHEMBL1243386 | 0.72 | GRM5 (0.56) | GRM5 | |
| SCHEMBL4150082 | 0.71 | GRM5 (0.46) | GRM5L3MBTL1 | |
| SCHEMBL3901343 | 0.70 | GRM5 (0.33) | GRM5 | |
| SCHEMBL31292025 | 0.69 | L3MBTL1 (0.47) | GRM5PLA2G4AL3MBTL1 | |
| SCHEMBL31487982 | 0.68 | GRM5 (0.33) | GRM5 | |
| SCHEMBL592502 | 0.68 | GRM5 (0.45) | GRM5L3MBTL1 | |
| SCHEMBL128971 | 0.67 | — | — | |
| SCHEMBL5048867 | 0.66 | ECE1 (0.42) | PLA2G4AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461811-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX Pharmaceuticals, Inc. (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2417134-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2012-02-15 | — | — | EP | disclosed |
| WO-2011017389-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |