SCHEMBL5783129

SCHEMBL5783129

C=C(C)C(=O)OCC([Si](C)(C)C)([Si](C)(C)C)[Si](C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.44
THRB P10828 1/20 0.42
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991742 0.80 THRB (0.48) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL57880 0.78 TSHR (0.52) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL5783939 0.76 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL18169552 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL16803285 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1902319 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL19197808 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL4457550 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL8965833 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL51592 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1299773-A4 SILICON-CONTAINING ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF FUJIFILM ELECTRONIC MATERIALS (US) 2006-06-21 EP disclosed
US-6783917-B2 HIGH RESOLUTION, DIMENSIONAL STABILITY; ELECTRONIC DEVICES WITH SMALLER FEATURE SIZES ARCH SPECIALTY CHEMICALS, INC. 2004-08-31 US disclosed
EP-1299773-A1 SILICON-CONTAINING ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2003-04-09 EP disclosed
US-20030065101-A1 Silicon-containing acetal protected polymers and photoresists compositions thereof ARCH SPECIALITY CHEMICALS, INC. 2003-04-03 US disclosed
WO-2002082184-A1 SILICON-CONTAINING ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2002-10-17 WO disclosed