SCHEMBL991742

SCHEMBL991742

C=C(C)C(=O)OCCC([Si](C)(C)C)([Si](C)(C)C)[Si](C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
TSHR P16473 3/20 0.47
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1554939 0.82 THRB (0.43) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL5783129 0.80 TSHR (0.45) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL9859987 0.80 THRB (0.41) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL26002227 0.79 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL22771295 0.78 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL4454148 0.78 THRB (0.46) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL8965485 0.78 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL438464 0.78 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL10349505 0.78 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL6232264 0.78 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8778278-B2 Non bio-adhesive polymer coating composition, articles and devices thereof GENERAL ELECTRIC COMPANY (US) 2014-07-15 US disclosed
US-20110015099-A1 NON BIO-ADHESIVE POLYMER COATING COMPOSITION, ARTICLES AND DEVICES THEREOF GENERAL ELECTRIC COMPANY (US) 2011-01-20 US disclosed
EP-1299773-A4 SILICON-CONTAINING ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF FUJIFILM ELECTRONIC MATERIALS (US) 2006-06-21 EP disclosed
US-6783917-B2 HIGH RESOLUTION, DIMENSIONAL STABILITY; ELECTRONIC DEVICES WITH SMALLER FEATURE SIZES ARCH SPECIALTY CHEMICALS, INC. 2004-08-31 US disclosed
EP-1299773-A1 SILICON-CONTAINING ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2003-04-09 EP disclosed
US-20030065101-A1 Silicon-containing acetal protected polymers and photoresists compositions thereof ARCH SPECIALITY CHEMICALS, INC. 2003-04-03 US disclosed
WO-2002082184-A1 SILICON-CONTAINING ACETAL PROTECTED POLYMERS AND PHOTORESISTS COMPOSITIONS THEREOF ARCH SPECIALTY CHEMICALS, INC. (US) 2002-10-17 WO disclosed