Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | UGCG | Q16739 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214525 | 0.88 | ACHE (0.44) | ACHERPS6KA2KDM4EALDH1A1NR1I2 | |
| SCHEMBL5784229 | 0.86 | ACHE (0.38) | ACHERPS6KA2KDM4EALDH1A1CYP1B1 | |
| SCHEMBL5784019 | 0.85 | — | — | |
| SCHEMBL5784447 | 0.84 | ACHE (0.41) | ACHERPS6KA2KDM4EALDH1A1CYP1B1 | |
| SCHEMBL6220121 | 0.84 | ACHE (0.41) | ACHERPS6KA2KDM4EALDH1A1NR1I2 | |
| SCHEMBL5783534 | 0.82 | HDAC1 (0.40) | ACHERPS6KA2KDM4EALDH1A1 | |
| SCHEMBL6218958 | 0.81 | ACHE (0.55) | ACHERPS6KA2 | |
| SCHEMBL5781219 | 0.81 | ACHE (0.39) | ACHERPS6KA2KDM4EALDH1A1 | |
| SCHEMBL5803057 | 0.80 | ACHE (0.39) | ACHERPS6KA2KDM4EALDH1A1 | |
| SCHEMBL5783190 | 0.80 | ACHE (0.40) | ACHERPS6KA2KDM4EALDH1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408962-B1 | SUBSTITUTED ISOINDOLES AND THE USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-03-15 | — | — | EP | disclosed |