Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578381 | 0.87 | — | — | |
| SCHEMBL578323 | 0.83 | MAOA (0.37) | KDM4EALDH1A1 | |
| SCHEMBL578087 | 0.76 | NPC1 (0.36) | ALDH1A1 | |
| SCHEMBL1232940 | 0.74 | TDP1 (0.33) | ALDH1A1 | |
| SCHEMBL578382 | 0.72 | MAOA (0.36) | ALDH1A1 | |
| SCHEMBL25412671 | 0.71 | PSMB8 (0.42) | ALDH1A1 | |
| SCHEMBL16516559 | 0.67 | ALOX15 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL577631 | 0.67 | — | — | |
| SCHEMBL27669614 | 0.66 | KDM4E (0.49) | KDM4EALDH1A1 | |
| SCHEMBL24181608 | 0.64 | HTR2C (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2461811-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX Pharmaceuticals, Inc. (US) | 2012-06-13 | — | — | EP | claimed |
| EP-2417134-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX Pharmaceuticals, Inc. (US) | 2012-02-15 | — | — | EP | claimed |
| WO-2011017389-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS USEFUL AGAINST VIRAL INFECTIONS, PARTICULARLY HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2011-02-10 | — | — | WO | claimed |
| WO-2010118078-A1 | MACROCYCLIC SERINE PROTEASE INHIBITORS | IDENIX PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | claimed |