Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720569 | 0.82 | ALDH1A1 (0.43) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL4696811 | 0.80 | HSD17B10 (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11754501 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7841883 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL197626 | 0.75 | KDM4E (0.45) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL5782916 | 0.75 | ALDH1A1 (0.42) | NPSR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL7068909 | 0.75 | ALDH1A1 (0.49) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL5782169 | 0.75 | DYRK1A (0.43) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL4328076 | 0.75 | DYRK1A (0.43) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL6883224 | 0.72 | HTT (0.46) | MAPTALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670794-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | Amgen Inc. (US) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005033105-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2005-04-14 | — | — | WO | disclosed |
| EP-0271893-B1 | AZO COMPOUNDS CONTAINING CYANOGEN GROUPS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |
| US-4889923-A | AZO compounds containing cyano and vinyl-sulfone groups, a process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-26 | — | — | US | disclosed |
| EP-0271893-A2 | Azo compounds containing cyanogen groups, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |
| US-4119776-A | Vinyl phthalide color formers | NCR CORPORATION (US) | 1978-10-10 | — | — | US | disclosed |
| US-4026883-A | MACHINE READABLE AND COPIABLE | NCR CORPORATION (US) | 1977-05-31 | — | — | US | disclosed |
| US-4016174-A | USED IN PRESSURE SENSITIVE RECORD MATERIALS AND MANIFOLD MARKING SYSTEMS | NCR CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |