SCHEMBL8720569

SCHEMBL8720569

CCN(CC)c1cc[c]c(NC(C)=O)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TSHR P16473 2/20 0.43
MAPT P10636 8/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
NOX1 Q9Y5S8 3/20 0.43
TP53 P04637 3/20 0.43
MCL1 Q07820 2/20 0.43
USP2 O75604 2/20 0.43
PKM P14618 1/20 0.43
MAPK1 P28482 1/20 0.43
GAA P10253 2/20 0.41
POLB P06746 1/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
HTT P42858 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
NFKB1 P19838 2/20 0.38
NFKB2 Q00653 2/20 0.38
RELA Q04206 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5783604 0.82 MAPT (0.44) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL6937148 0.76 MAOA (0.40) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL4328076 0.75 DYRK1A (0.43) ALDH1A1MAPTMEN1KMT2APKM
SCHEMBL11754501 0.73 ALDH1A1 (0.47) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL4696811 0.73 HSD17B10 (0.47) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL7841883 0.73 ALDH1A1 (0.47) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL8850272 0.72 THRA (0.36) LMNAESRRGCNR2
SCHEMBL5782916 0.71 ALDH1A1 (0.42) ALDH1A1MEN1KMT2ATP53MAPK1
SCHEMBL5782169 0.71 DYRK1A (0.43) ALDH1A1MAPTPKMGAARAB9A
SCHEMBL197626 0.71 KDM4E (0.45) ALDH1A1MEN1KMT2AMAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4101540-A USEFUL FOR DYEING ACRYLONITRILE POLYMERS OR ACID-MODIFIED POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US claimed
US-5814580-A FORMING A CHELATE DYE BY THE REACTION OF AN AZOMETHINE DYE WITH A METAL-ION CONTAINING COMPOUND; EXCELLENT LIGHT FASTNESS KONICA CORPORATION (JP) 1998-09-29 US disclosed
EP-0732220-A1 Thermal transfer recording material KONICA CORPORATION (JP) 1996-09-18 EP disclosed
US-4670548-A Sulfo-group-containing trisazo dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US disclosed
EP-0012350-B1 AZO DYESTUFFS, THEIR PREPARATION AND THEIR USE IN THE DYEING OF N-CONTAINING MATERIALS BAYER AG (DE) 1982-04-07 EP disclosed
EP-0017841-A1 Polyazo dyestuffs and their use in dyeing fibrous materials containing nitrogen BAYER AG (DE) 1980-10-29 EP disclosed
US-4104270-A Process for the manufacture of aromatic phosphonates IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1978-08-01 US disclosed