SCHEMBL5784397

SCHEMBL5784397

C=C(C[Si](C)(C)O[SiH2]C)C(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TSHR P16473 1/20 0.38
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
GLO1 Q04760 1/20 0.32
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
PKM P14618 1/20 0.30
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30
THRB P10828 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL599743 0.77 ALDH1A1 (0.45) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL323091 0.71
SCHEMBL15393154 0.70 ALDH1A1 (0.45) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL4623059 0.69 ALDH1A1 (0.48) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL17023657 0.68 ALDH1A1 (0.44) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL14533248 0.68 ALDH1A1 (0.52) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL35720 0.68
SCHEMBL7037635 0.67 ALDH1A1 (0.47) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL4792849 0.67 ALDH1A1 (0.47) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL36653 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1714182-A2 HYBRID CONTACT LENS SYSTEM AND METHOD Quarter Lambda Technologies Inc. (US) 2006-10-25 EP disclosed
WO-2005079290-A2 HYBRID CONTACT LENS SYSTEM AND METHOD SYNERGEYES, INC. (US) 2005-09-01 WO disclosed