SCHEMBL599743

SCHEMBL599743

C=C(C[Si](C)(C)C)C(=O)OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
TSHR P16473 1/20 0.45
MAPT P10636 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GLO1 Q04760 1/20 0.38
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
THRB P10828 1/20 0.35
EGLN1 Q9GZT9 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1219576 0.83 TSHR (0.40) ALDH1A1TSHRLMNAGAATHRB
SCHEMBL1218078 0.80 TSHR (0.50) ALDH1A1TSHRNPSR1LMNATHRB
SCHEMBL5784397 0.77 ALDH1A1 (0.38) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL1217501 0.77 TSHR (0.61) ALDH1A1TSHRNPSR1LMNA
SCHEMBL9156218 0.77 ALDH1A1 (0.44) ALDH1A1TSHREGLN1
SCHEMBL17023657 0.77 ALDH1A1 (0.44) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL35720 0.77
SCHEMBL14533248 0.77 ALDH1A1 (0.52) ALDH1A1TSHRMAPTNPSR1GLO1
SCHEMBL5395018 0.75 THRB (0.31) TSHRTHRB
SCHEMBL36653 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042870-A1 BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2026-02-12 US claimed
US-11945883-B2 Binder compositions and uses thereof KNAUF INSULATION SPRL (BE) 2024-04-02 US claimed
EP-3368593-B1 IMPROVED BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2023-12-06 EP claimed
US-20220306769-A1 Binder Compositions and Uses Thereof KNAUF INSULATION SPRL (BE) 2022-09-29 US claimed
US-11325985-B2 Binder compositions and uses thereof KNAUF INSULATION SPRL (BE) 2022-05-10 US claimed
CN-110917075-A Prickly heat-removing mosquito-repelling infant skin-care talcum powder and preparation method thereof 宁波洁美日化科技有限公司 2020-03-27 CN claimed
WO-2019034597-A1 FORCE-RESPONSIVE POLYMERSOMES AND NANOREACTORS; PROCESSES UTILIZING THE SAME ADOLPHE MERKLE INSTITUTE, UNIVERSITY OF FRIBOURG (CH) 2019-02-21 WO claimed
US-20180319901-A1 Improved Binder Compositions and Uses Thereof KNAUF INSULATION SPRL (BE) 2018-11-08 US claimed
EP-3368593-A1 IMPROVED BINDER COMPOSITIONS AND USES THEREOF Knauf Insulation SPRL (BE) 2018-09-05 EP claimed
WO-2018017570-A1 A HAIR STRAIGHTENING AND STYLING COMPOSITION, PROCESS FOR PREPARING THE SAME AND METHOD OF USE THEREOF ISP INVESTMENTS LLC (US) 2018-01-25 WO claimed
WO-2017072186-A1 IMPROVED BINDER COMPOSITIONS AND USES THEREOF KNAUF INSULATION SPRL (BE) 2017-05-04 WO claimed
US-5932675-A Free-radical chain transfer polymerization process COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-08-03 US claimed
US-5385996-A Control of molecular weight and end-group functionality of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1995-01-31 US claimed
US-20260139091-A1 MULTI-VALENT POLYMERIZABLE COMPOSITIONS AND METHODS OF PRODUCING AND USING THE SAME ALIGN TECH INC (US) 2026-05-21 US disclosed
EP-4740970-A2 MULTI-LAYERED BIOMIMETIC OSTEOCHONDRAL IMPLANTS Hyalex Orthopaedics, Inc. (US) 2026-05-13 EP disclosed
EP-4362856-B1 MULTI-LAYERED BIOMIMETIC OSTEOCHONDRAL IMPLANTS HYALEX ORTHOPAEDICS INC (US) 2026-05-06 EP disclosed
US-5385996-A Control of molecular weight and end-group functionality of polymers COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1995-01-31 US disclosed
EP-0333758-A4 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. COMMW SCIENT IND RES ORG (AU) 1990-05-14 EP disclosed
EP-0333758-A1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS. COMMW SCIENT IND RES ORG (AU) 1989-09-27 EP disclosed
WO-1988004304-A1 CONTROL OF MOLECULAR WEIGHT AND END GROUP FUNCTIONALITY OF POLYMERS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1988-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042870-A1 BINDER COMPOSITIONS AND USES THEREOF SMCHD1, VCL, FGB ALDH1A1 1900/4885TSHR 4450/4885MAPT 134/4885
US-20260139091-A1 MULTI-VALENT POLYMERIZABLE COMPOSITIONS AND METHODS OF PRODUCING AND USING THE SAME SMCHD1, PBRM1, VCL ALDH1A1 3983/4885TSHR 4190/4885MAPT 325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.