SCHEMBL578470

SCHEMBL578470

CCC([O])(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4488934 0.78
SCHEMBL5532955 0.75
SCHEMBL9868078 0.75
SCHEMBL832257 0.72
SCHEMBL4913662 0.72
SCHEMBL21812089 0.72
SCHEMBL22731 0.70
SCHEMBL1349068 0.70
SCHEMBL28183968 0.70
SCHEMBL11625638 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117327000-A Biphenyl tetrahydropyrrole compound and preparation method and application thereof 海南因瑞生物医药科技有限公司 2024-01-02 CN claimed
CN-115232129-B PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2023-12-01 CN claimed
CN-115232129-A PARP1 selective inhibitor and preparation method and application thereof 上海闻耐医药科技有限公司 2022-10-25 CN claimed
WO-2024149728-A1 SUBSTITUTED (HETERO)ANILINES AND THEIR USE ASTRAZENECA AB (SE) 2024-07-18 WO disclosed
WO-2024137984-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS, INC. (US) 2024-06-27 WO disclosed
EP-4373809-A1 SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS Novartis AG (CH) 2024-05-29 EP disclosed
EP-4373814-A1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES Novartis AG (CH) 2024-05-29 EP disclosed
CN-117980292-A Substituted pyridone compounds for the treatment of orthomyxoviral infections 诺华股份有限公司 2024-05-03 CN disclosed
WO-2024091489-A1 FUSED AZINES AS DYNAMIN-1-LIKE PROTEIN INHIBITORS AND USES THEREOF MITOBRIDGE, INC. (US) 2024-05-02 WO disclosed
EP-4041725-B1 QUINOLINE COMPOUNDS AND COMPOSITIONS FOR INHIBITING EZH2 AS A TREATMENT FOR CANCER DISEASES NOVARTIS AG (CH) 2024-03-27 EP disclosed
WO-2024051696-A1 COMPOUND FOR RNA CAPPING AND USE THEREOF 广州市恒诺康医药科技有限公司 2024-03-14 WO disclosed
EP-0110576-B1 IONIZING RADIATION-SENSITIVE MATERIAL AND ITS USE FOR PREPARING A PATTERN JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1988-01-07 EP disclosed
US-4623609-A HALOGENATED OLEFIN AROMATIC POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-11-18 US disclosed
US-4604460-A ANTIBIOTICS, BACTERICIDES SHIONOGI & CO., LTD. (JP) 1986-08-05 US disclosed
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US disclosed
US-4504659-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1985-03-12 US disclosed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US disclosed
EP-0110576-A2 Ionizing radiation-sensitive material and its use for preparing a pattern JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1984-06-13 EP disclosed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US disclosed
US-4366316-A FROM OXAZOLINOAZETIDINONE AND ACID SHIONOGI & CO., LTD. (JP) 1982-12-28 US disclosed