⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671173 | 0.82 | — | — | |
| SCHEMBL4396097 | 0.82 | HSD17B10 (0.34) | — | |
| SCHEMBL2670662 | 0.80 | DNM1 (0.46) | — | |
| SCHEMBL4400535 | 0.80 | CA1 (0.30) | — | |
| SCHEMBL4392879 | 0.80 | LMNA (0.31) | — | |
| SCHEMBL6869009 | 0.79 | — | — | |
| SCHEMBL2671071 | 0.79 | — | — | |
| SCHEMBL23149779 | 0.78 | DNM1 (0.50) | — | |
| SCHEMBL11180663 | 0.78 | DNM1 (0.50) | — | |
| SCHEMBL7858965 | 0.78 | DNM1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140212365-A9 | SKIN LIGHTENING COMPOSITIONS | NIKI YOKO (JP) | 2014-07-31 | — | — | US | claimed |
| US-20140112877-A1 | SKIN LIGHTENING COMPOSITIONS | NIKI YOKO (JP) | 2014-04-24 | — | — | US | claimed |
| EP-2521531-A2 | SKIN LIGHTENING COMPOSITIONS | ELC Management LLC (US) | 2012-11-14 | — | — | EP | claimed |
| US-8143408-B2 | N-(8-heteroaryltetrahydronaphtalene-2yl) or N-(5-heteroarylchromane-3-yl) carboxamide derivatives for the treatment of pain | ASTRAZENECA AB (SE) | 2012-03-27 | — | — | US | claimed |
| US-20110171149-A1 | Skin Lightening Compositions | ELC MANAGEMENT LLC | 2011-07-14 | — | — | US | claimed |
| WO-2011085015-A2 | SKIN LIGHTENING COMPOSITIONS | ELC MANAGEMENT LLC (US) | 2011-07-14 | — | — | WO | claimed |
| US-20100137322-A1 | NOVEL N-(8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N-(5-HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2010-06-03 | — | — | US | claimed |
| EP-2158198-A2 | NOVEL N- (8HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | claimed |
| WO-2008130320-A2 | NOVEL N- (8-HETEROARYLTETRAHYDRONAPHTALENE-2YL) OR N- (5- HETEROARYLCHROMANE-3-YL) CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| EP-4396163-A1 | HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS | BASF SE (DE) | 2024-07-10 | — | — | EP | disclosed |
| EP-4396173-A1 | HERBICIDAL MALONAMIDES CONTAINING A CONDENSED RING SYSTEM | BASF SE (DE) | 2024-07-10 | — | — | EP | disclosed |
| EP-4392403-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2024-07-03 | — | — | EP | disclosed |
| EP-4391808-A1 | HERBICIDAL MALONAMIDES | BASF SE (DE) | 2024-07-03 | — | — | EP | disclosed |
| EP-4374877-A2 | PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-29 | — | — | EP | disclosed |
| EP-0213617-A2 | Digestive tract contractile motion stimulant | KITASATO KENKYUSHO (JP) | 1987-03-11 | — | — | EP | disclosed |
| WO-1986007059-A2 | OXODIAZINE COMPOUNDS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-12-04 | — | — | WO | disclosed |
| EP-0005321-B1 | DERIVATIVES OF N-TRIFLUOROACETYL N-PHOSPHONOMETHYLGLYCINE DICHLORIDE, THEIR PREPARATION AND THEIR USE AS HERBICIDES | MONSANTO COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4199345-A | Derivatives of N-trifluoroacetyl-N-phosphonomethylglycine dichloride | MONSANTO COMPANY (US) | 1980-04-22 | — | — | US | disclosed |
| EP-0005321-A1 | Derivatives of N-trifluoroacetyl N-phosphonomethylglycine dichloride, their preparation and their use as herbicides | MONSANTO COMPANY (US) | 1979-11-14 | — | — | EP | disclosed |
| US-3936438-A | INOTROPIC | WARNER-LAMBERT COMPANY (US) | 1976-02-03 | — | — | US | disclosed |