SCHEMBL578653

SCHEMBL578653

Cc1cccc(-c2ccccc2S(N)(=O)=O)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.47
CA1 P00915 9/20 0.47
CA9 Q16790 9/20 0.47
CA12 O43570 4/20 0.47
CA4 P22748 4/20 0.44
CA7 P43166 4/20 0.44
CA6 P23280 3/20 0.44
CA5A P35218 3/20 0.44
CA5B Q9Y2D0 2/20 0.44
CYP2C9 P11712 1/20 0.44
CA14 Q9ULX7 1/20 0.44
STAT3 P40763 1/20 0.42
ALOX5AP P20292 1/20 0.39
FEN1 P39748 1/20 0.39
SCN9A Q15858 1/20 0.39
CDK2 P24941 1/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
TRPA1 O75762 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5808223 0.89 CA2 (0.43) CA2CA1CA9CA12CA4
SCHEMBL21408104 0.87 CA2 (0.42) CA2CA1CA9CA12CA4
SCHEMBL1116406 0.86 CA2 (0.56) CA2CA1CA9CA12CA4
SCHEMBL4435159 0.85 CA2 (0.51) CA2CA1CA9CA12CA4
Ammonia Solution, Strong SCHEMBL28645552 0.85 CA2 (0.55) CA2CA1CA9CA12CA4
Hydrochloric Acid SCHEMBL5808145 0.84 CA2 (0.50) CA2CA1CA9CA12CA4
Hydrochloric Acid SCHEMBL5808221 0.84 STAT3 (0.49) CA2CA1CA9CA12CA4
SCHEMBL401308 0.82 CA2 (0.47) CA2CA1CA9CA12CA4
SCHEMBL31310995 0.82 CA2 (0.47) CA2CA1CA9CA12CA4
SCHEMBL1080972 0.82 CA2 (0.61) CA2CA1CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109863146-A Aryl-linking compound as immunomodulator 百时美施贵宝公司 2019-06-07 CN claimed
EP-2417198-A1 POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES Rhodia Opérations (FR) 2012-02-15 EP claimed
WO-2010115951-A1 POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES RHODIA OPERATIONS (FR) 2010-10-14 WO claimed
EP-2417198-A1 POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES Rhodia Opérations (FR) 2012-02-15 EP disclosed
WO-2010115951-A1 POLYAMIDE MATERIAL HAVING HIGH FLUID BARRIER PROPERTIES RHODIA OPERATIONS (FR) 2010-10-14 WO disclosed