SCHEMBL401308

SCHEMBL401308

Cc1cccc(S(N)(=O)=O)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 10/20 0.47
CA1 P00915 8/20 0.47
CA9 Q16790 8/20 0.47
CA12 O43570 4/20 0.46
CA4 P22748 3/20 0.46
CA6 P23280 3/20 0.46
CA7 P43166 3/20 0.46
CA5A P35218 3/20 0.46
CA5B Q9Y2D0 2/20 0.46
CYP2C9 P11712 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CDK2 P24941 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 2/20 0.44
TRPA1 O75762 1/20 0.44
ATM Q13315 1/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31310995 1.00 CA2 (0.47) CA2CA1CA9CA12CA4
Hydrochloric Acid SCHEMBL1017217 0.98 CA2 (0.45) CA2CA1CA9CA12CA4
Hydrochloric Acid SCHEMBL19211699 0.98 CA2 (0.45) CA2CA1CA9CA12CA4
SCHEMBL10808580 0.88 CA2 (0.52) CA2CA1CA9CA12CA4
Phenol SCHEMBL5134435 0.87 CDK2 (0.44) CA2CA1CA9CA12CA4
Hydrochloric Acid SCHEMBL5808223 0.86 CA2 (0.43) CA2CA1CA9CA12CA4
Trifluoroacetic Acid SCHEMBL3610284 0.84 ALDH1A1 (0.42) CA2CA1CA9CA12CA5A
SCHEMBL578653 0.82 CA2 (0.47) CA2CA1CA9CA12CA4
SCHEMBL4435159 0.82 CA2 (0.51) CA2CA1CA9CA12CA4
SCHEMBL7369 0.81 CA2 (0.56) CA2CA1CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 603 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630529-B2 GCN2 modulator compounds Alesta Therapeutics BV (NL) 2026-05-19 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-4200298-B1 1H-PYRROLO[3,2-C]PYRIDINE AND 1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS BRISTOL MYERS SQUIBB CO (US) 2025-05-21 EP claimed
EP-3697410-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USES TEIJIN PHARMA LTD (JP) 2024-12-18 EP claimed
EP-3829520-B1 HALOALLYLAMINE SULFONE DERIVATIVE INHIBITORS OF LYSYL OXIDASES AND USES THEREOF SYNTARA LTD (AU) 2024-11-27 EP claimed
EP-3792256-B1 PYRIDINE COMPOUNDS AS PI3K-GAMMA INHIBITORS INCYTE CORP (US) 2024-10-23 EP claimed
US-20240102976-A1 METHOD FOR SCREENING PESTICIDE RESIDUES IN MEDICINE FOOD HOMOLOGY CHARACTERISTIC AGRICULTUREAL PRODUCTS CHANGCHUN CUSTOMS TECHNOLOGY CENTER (CN) 2024-03-28 US claimed
CN-117462656-A ROS-based periodontal ligament stem cell local protective agent and preparation method thereof 首都医科大学附属北京口腔医院 2024-01-30 CN claimed
EP-3483166-B1 IMIDAZOOXAZOLE DERIVATIVE HAVING ANTITUMOR EFFECT, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME KOREA INST SCI & TECH (KR) 2023-11-01 EP claimed
EP-4013495-B1 ARYLSULFONAMIDE DERIVATIVES AS MGLUR4 NEGATIVE ALLOSTERIC MODULATORS HOFFMANN LA ROCHE (CH) 2023-09-27 EP claimed
WO-2004032882-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2004-04-22 WO claimed
EP-1401825-A2 THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION Shire Biochem Inc. (CA) 2004-03-31 EP claimed
WO-2003082205-A2 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2003-10-09 WO claimed
WO-2002100851-A2 THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION SHIRE BIOCHEM INC. (CA) 2002-12-19 WO claimed
JP-2002540099-A 2002-11-26 JP claimed
EP-1163221-A1 SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2001-12-19 EP claimed
WO-2000056712-A1 SULFONAMIDE DERIVATIVES AS 5-HT7 RECEPTOR ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 2000-09-28 WO claimed
EP-0496119-A1 Flame retardant thermoplastic moulding compounds with higher fluidity BASF Aktiengesellschaft (DE) 1992-07-29 EP claimed
EP-0034432-B1 SULFAMOYL-SUBSTITUTED PHENETHYLAMINE DERIVATIVES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS, CONTAINING THEM YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-04-25 EP claimed
US-4123376-A AROMATIC SULFONAMIDE COLGATE-PALMOLIVE COMPANY (US) 1978-10-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630529-B2 GCN2 modulator compounds NR3C1, GCN1, EIF2AK4 CA2 1341/4885CA1 3553/4885CA9 2371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.