SCHEMBL5787004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6430612	0.87	LCK (0.45)	LCKFYNKMT2AMEN1KDM4E
	SCHEMBL5785487	0.83	AAK1 (0.48)	MTNR1AMTNR1BAAK1P2RX7KMT2A
	SCHEMBL31662566	0.83	AAK1 (0.48)	MTNR1AMTNR1BAAK1P2RX7KMT2A
	SCHEMBL5801045	0.77	AAK1 (0.36)	MTNR1AMTNR1BAAK1KMT2AMEN1
	SCHEMBL4804361	0.73	ALDH1A1 (0.50)	KMT2AMEN1KDM4EALDH1A1LMNA
	Carbamic Acid SCHEMBL31281228	0.72	AAK1 (0.42)	MTNR1AMTNR1BAAK1LCKFYN
	SCHEMBL31736070	0.69	AAK1 (0.52)	AAK1LCKKMT2AMEN1POLB
	SCHEMBL24097858	0.69	ALDH1A1 (0.40)	LCKFYNP2RX7KMT2AKDM4E
	SCHEMBL25853890	0.68	EGFR (0.34)	LCKFYNP2RX7KMT2AMEN1
	SCHEMBL28892489	0.68	AAK1 (0.46)	MTNR1AMTNR1BAAK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.