Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.38 |
| ▸ | TCF7L2 | Q9NQB0 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940639 | 0.85 | CTNNB1 (0.51) | CTNNB1TCF7L2 | |
| SCHEMBL940842 | 0.84 | FLT3 (0.47) | NPC1RAB9AMAPTLMNACTNNB1 | |
| SCHEMBL940614 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6613383 | 0.78 | CTNNB1 (0.47) | MEN1KMT2ALMNACTNNB1TCF7L2 | |
| SCHEMBL6489855 | 0.78 | ADORA3 (0.49) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL941803 | 0.76 | ADORA2A (0.43) | NPC1RAB9AMAPTLMNACTNNB1 | |
| SCHEMBL6479650 | 0.76 | MEN1 (0.54) | MEN1KMT2ANPC1RAB9ATSHR | |
| SCHEMBL940906 | 0.76 | ADORA2A (0.43) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL942090 | 0.74 | MAPT (0.47) | MEN1KMT2AMAPTTSHRLMNA | |
| SCHEMBL27683894 | 0.73 | KDM4E (0.40) | MEN1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663982-A1 | AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | Sanofi-Aventis (FR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005009969-A1 | AMINOQUINOLINE DERIVATIVES AND THEIR USE AS ADENOSINE A3 LIGANDS | SANOFI-AVENTIS (FR) | 2005-02-03 | — | — | WO | disclosed |