SCHEMBL5788342

SCHEMBL5788342

NC(=O)CC[C@H](N)C(=O)N1CC2CC2C1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
KMT2A Q03164 1/20 0.47
ARG1 P05089 2/20 0.43
DPP4 P27487 10/20 0.40
DPP8 Q6V1X1 6/20 0.37
DPP9 Q86TI2 6/20 0.37
DPP7 Q9UHL4 7/20 0.36
PDK2 Q15119 1/20 0.34
FAP Q12884 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5788237 0.89 DPP7 (0.44) ALOX15BLMPMP22KMT2AARG1
SCHEMBL5790370 0.82 DPP4 (0.47) ALOX15BLMPMP22KMT2AARG1
SCHEMBL5789348 0.82 DPP4 (0.47) ALOX15BLMPMP22KMT2AARG1
SCHEMBL5790371 0.82 DPP4 (0.47) ALOX15BLMPMP22KMT2AARG1
SCHEMBL1072126 0.78 ALOX15 (0.50) ALOX15BLMPMP22KMT2AARG1
SCHEMBL1509740 0.78 ALOX15 (0.50) ALOX15BLMPMP22KMT2AARG1
SCHEMBL5791904 0.77 ALOX15 (0.42) ALOX15BLMPMP22KMT2AARG1
Hydrochloric Acid SCHEMBL4956521 0.76 ALOX15 (0.48) ALOX15BLMPMP22KMT2AARG1
SCHEMBL6742082 0.76 DPP7 (0.50) ALOX15BLMPMP22KMT2AARG1
Hydrochloric Acid SCHEMBL5702744 0.76 ALOX15 (0.48) ALOX15BLMPMP22KMT2AARG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622870-A2 GLUTAMINYL BASED DP IV-INHIBITORS Prosidion Ltd. (GB) 2006-02-08 EP disclosed
WO-2004099134-A2 GLUTAMINYL BASED DP IV-INHIBITORS PROSIDION LTD. (GB) 2004-11-18 WO disclosed
US-20040229848-A1 Glutaminyl based DP IV-inhibitors PROSIDION LIMITED (GB) 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040229848-A1 Glutaminyl based DP IV-inhibitors DPP4, DPP3, DNPEP ALOX15 4131/4885BLM 3796/4885PMP22 2783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.